SynthesisHypertension research : official journal of the Japanese Society of Hypertension2022
Benefits of continuous positive airway pressure on blood pressure in patients with hypertension and obstructive sleep apnea: a meta-analysis.
Synthesis in Hypertension research : official journal of the Japanese Society of Hypertension, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Effects of Continuous Positive Airway Pressure on Surrogate, Intermediate, and Functional Cardiovascular Outcomes in Obstructive Sleep Apnea: An Umbrella Review of Systematic Reviews and Meta-Analyses.Medicina (Kaunas, Lithuania) · 2026Pooled it
- Efficacy and safety of continuous positive airway pressure on blood pressure in patients with obstructive sleep apnea: an overview of systematic reviews and meta analyses.Frontiers in medicine · 2026Pooled it
- Benefits of ozone on mortality in patients with COVID-19: A systematic review and meta-analysis.Complementary therapies in medicine · 2023Pooled it
- Benefits of tolvaptan on early dyspnea relief in patients with acute heart failure: A meta-analysis.Clinical cardiology · 2022Pooled it
- Obstructive Sleep Apneas and Cardiovascular Diseases.Clocks & sleep · 2026Review
- Predicting Significant Blood Pressure Reduction Through Ambulatory Blood Pressure Monitoring in Patients With Obstructive Sleep Apnea Treated With Continuous Positive Airway Pressure.The clinical respiratory journal · 2026Article
- The Japanese Society of Hypertension Guidelines for the management of elevated blood pressure and hypertension 2025 (JSH2025).Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Resistant Hypertension: Integration of Novel Agents and Interventional Approaches in Clinical Practice.Reviews in cardiovascular medicine · 2026Review
- Effect Heterogeneity of CPAP on MACE by Nocturnal Hypoxia Burden in Older Adults OSAS: A Propensity Score Matching Study.Clinical interventions in aging · 2026Article
- Cardiovascular effects of obstructive sleep apnoea and effects of continuous positive airway pressure therapy: evidence from different study models.ERJ open research · 2025Review
- Outpatient management of essential hypertension: a review based on the latest clinical guidelines.Annals of medicine · 2024Review
- Achieving adherence to positive airway pressure in commercial drivers using an employer-mandated remote management programme.ERJ open research · 2024Article
- Obstructive sleep apnea -related hypertension: a review of the literature and clinical management strategy.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Review
- The Role of Sleep in Cardiovascular Disease.Current atherosclerosis reports · 2024Review
- Hypoxia-Induced Insulin Resistance Mediates the Elevated Cardiovascular Risk in Patients with Obstructive Sleep Apnea: A Comprehensive Review.Reviews in cardiovascular medicine · 2024Review
- Obstructive sleep apnea and non-dipper: epiphenomena or risks of Alzheimer's disease?: a review from the HOPE Asia Network.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Review
- Sleep and cardiovascular disease.Emerging topics in life sciences · 2023Review
- A Narrative Review of the Association of Obstructive Sleep Apnea with Hypertension: How to Treat Both When They Coexist?Journal of clinical medicine · 2023Review
- The combination of nondipper pulse rate pattern and nighttime high pulse rate variability is associated with an increase of brain natriuretic peptide: the J-HOP study.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Article
- A Review of a Recent Meta-Analysis Study on Obstructive Sleep Apnea.Journal of rhinology : official journal of the Korean Rhinologic Society · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This meta-analysis was performed to determine the effects of continuous positive airway pressure (CPAP) on blood pressure (BP) in patients with systemic hypertension and obstructive sleep apnea (OSA). A systematic search was conducted using PubMed, Embase, Web of Science, Cochrane Library, and clinicaltrials.gov, without language restrictions. Randomized controlled trials on the treatment of hypertension and OSA with CPAP, compared with sham CPAP or no CPAP, were reviewed. Studies were pooled to obtain weighted mean differences (WMDs) with 95% confidence intervals (CIs). Nineteen trials (enrolling 1904 participants) met the inclusion criteria. CPAP had significant effects on 24-h systolic blood pressure (SBP) (WMD -5.01 mmHg, 95% CI -6.94 to -3.08; P < 0.00001), 24-h diastolic blood pressure (DBP) (WMD -3.30 mmHg, 95% CI -4.32 to -2.28; P < 0.00001), daytime SBP (WMD -4.34 mmHg, 95% CI -6.27 to -2.40; P < 0.0001), daytime DBP (WMD -2.97 mmHg, 95% CI -3.99 to -1.95; P < 0.00001), nighttime SBP (WMD -3.55 mmHg, 95% CI -5.08 to -2.03; P < 0.00001), nighttime DBP (WMD -2.33 mmHg, 95% CI -3.27 to -1.40; P < 0.00001), office SBP (WMD -3.67 mmHg, 95% CI -5.76 to -1.58; P = 0.0006), office DBP (WMD -2.61 mmHg, 95% CI -4.25 to -0.97; P = 0.002), and heart rate (WMD -2.79 beats/min, 95% CI -4.88 to -0.71; P = 0.009). CPAP treatment was associated with BP reduction in patients with systemic hypertension and OSA, except when the follow-up period was shorter than 3 months.
Indexed as
Identifiers
35701490What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.