ArticleScientific reports2022
Genome wide association study identifies novel candidate genes for growth and body conformation traits in goats.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Genome-Wide Differentiation, Inbreeding, and Candidate Selection Loci in Local Vietnamese Pig Breeds.International journal of molecular sciences · 2026Article
- Host genetic architecture and gut microbiota cooperatively regulate early growth in goats.Animal microbiome · 2026Article
- On the genetic origins of phenotypes in genome-wide association studies: the SAFE-hBMC bioinformatics · 2026Article
- Whole-Genome Sequencing Reveals Breed-Specific SNPs, Indels, and Signatures of Selection in Royal White and White Dorper Sheep.Animals : an open access journal from MDPI · 2026Article
- Population structure and genome-wide association study of body conformation traits of two native goat breeds in China.Animal bioscience · 2026Article
- Decoding the DNA of Anatolian water buffalo by genome-wide discoveries for body size and ultrasound carcass traits.BMC veterinary research · 2025Article
- Whole-genome sequencing reveals complex structural variations at a major locus linked to pigmented spot sizes in Tianfu goats.BMC genomics · 2025Article
- Resequencing Composite Kazakh Whiteheaded Cattle: Insights into Ancestral Breed Contributions, Selection Signatures, and Candidate Genetic Variants.Animals : an open access journal from MDPI · 2025Article
- Genome-wide association study identifies candidate genes affecting body conformation traits of Zhongwei goat.BMC genomics · 2025Article
- Prediction of carcass weight using the morphometry of ankle bones in hair goats.Veterinary medicine and science · 2024Article
- Genome-Wide Association Study of Body Conformation Traits in Tashi Goats (Animals : an open access journal from MDPI · 2024Article
- Genome-Wide Association Study of Milk Composition in Karachai Goats.Animals : an open access journal from MDPI · 2024Article
- Genetic characterization of cashmere goat (Frontiers in genetics · 2024Article
- Genomic Selection for Live Weight in the 14th Month in Alpine Merino Sheep Combining GWAS Information.Animals : an open access journal from MDPI · 2023Article
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- Genome-Wide Association and Pathway Analysis of Carcass and Meat Quality Traits in Karachai Young Goats.Animals : an open access journal from MDPI · 2023Article
- A genome-wide association study of morphometric traits in dromedaries.Veterinary medicine and science · 2023Article
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Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pakistan is third largest country in term of goat population with distinct characteristics of breeds and estimated population of 78.2 million. Punjab province has 37% of country's total population with seven important documented goat breeds namely Beetal, Daira Din Pannah, Nachi, Barbari, Teddi, Pahari and Pothwari. There is paucity of literature on GWAS for economically important traits i.e., body weight and morphometric measurements. Therefore, we performed GWAS using 50 K SNP Chip for growth in term of age adjusted body weight and morphometric measurements in order to identify genomic regions influencing these traits among Punjab goat breeds. Blood samples were collected from 879 unrelated animals of seven goat breeds along with data for body weight and morphometric measurements including body length, body height, pubic bone length, heart girth and chest length. Genomic DNA was extracted and genotyped using 50 K SNP bead chip. Association of genotypic data with the phenotypic data was performed using Plink 1.9 software. Linear mixed model was used for the association study. Genes were annotated from Capra hircus genome using assembly ARS1. We have identified a number of highly significant SNPs and respective candidate genes associated with growth and body conformation traits. The functional aspects of these candidate genes suggested their potential role in body growth. Moreover, pleiotropic effects were observed for some SNPs for body weight and conformation traits. The results of current study contributed to a better understanding of genes influencing growth and body conformation traits in goat.
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