Evidence map›Paper›PMID 35701428›Full record

ArticleScientific data2022

A longitudinal resource for studying connectome development and its psychiatric associations during childhood.

Russell H Tobe, Anna MacKay-Brandt, Ryan Lim, Melissa Kramer, Melissa M Breland, Lucia Tu, Yiwen Tian, Kristin Dietz Trautman, Caixia Hu, Raj Sangoi and 8 more

Open access · goldAbstract readDataset
In one paragraph

Article in Scientific data, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
18.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 49 citations in OpenAlex.

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  10. Considerations for conducting developmental neuroimaging research on mental health topics.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 1 country.

Russell H TobeNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA. russell.tobe@nki.rfmh.org.ORCID http://orcid.org/0000-0002-7738-8344
Anna MacKay-BrandtNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA.
Ryan LimNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA.
Melissa KramerNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA.
Melissa M BrelandNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA.
Lucia TuNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA.ORCID http://orcid.org/0000-0002-2300-3007
Yiwen TianNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA.
Kristin Dietz TrautmanNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA.
Caixia HuNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA.
Raj SangoiNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA.
Lindsay AlexanderCenter for the Developing Brain, Child Mind Institute, New York, NY, 10022, USA.
Vilma GabbayNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA.
F Xavier CastellanosNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA.
Bennett L LeventhalUniversity of Chicago, Chicago, IL, 60637, USA.
R Cameron CraddockDepartment of Diagnostic Medicine, The University of Texas at Austin Dell Medical School, Austin, TX, 78712, USA.ORCID http://orcid.org/0000-0002-4950-1303
Stanley J ColcombeNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA.
Alexandre R FrancoNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA.
Michael P MilhamNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA. michael.milham@childmind.org.ORCID http://orcid.org/0000-0003-3532-1210
Nathan Kline Institute for Psychiatric Research · USChild Mind Institute · USThe University of Texas at Austin · USUniversity of Chicago · US

Funding

Biobehavioral Predictors of Illness Progression in Adolescent DepressionR01MH120601 · NIMH · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GABBAY, VILMA · 2020 to 2024
$3.9M
Longitudinal Discovery of Brain Developmental TrajectoriesU01MH099059 · NIMH · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · PI MILHAM, MICHAEL PETER · 2013 to 2017
$3.7M
Mapping interindividual variation in the aging connectomeR01AG047596 · NIA · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · PI COLCOMBE, STAN J, MILHAM, MICHAEL PETER · 2015 to 2019
$3.1M
Discovery Science of Human Brain Function Across the LifespanR01MH094639 · NIMH · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · PI MILHAM, MICHAEL PETER · 2011 to 2014
$2.7M
Real-time fMRI Neurofeedback Based Stratification of Default Network RegulationR01MH101555 · NIMH · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · PI CRADDOCK, RICHARD CAMERON · 2013 to 2016
$2.6M
NIA NIH HHS R01 AG047596NIMH NIH HHS R01 MH094639NIMH NIH HHS R01 MH101555NIMH NIH HHS R01 MH120601NIMH NIH HHS U01 MH099059U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01AG047596U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01MH101555U.S. Department of Health & Human Services | National Institutes of Health (NIH) U01MH099059U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) BRAINS R01MH094639-01U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) R01AG047596
6 · The paper itself

Abstract

Most psychiatric disorders are chronic, associated with high levels of disability and distress, and present during pediatric development. Scientific innovation increasingly allows researchers to probe brain-behavior relationships in the developing human. As a result, ambitions to (1) establish normative pediatric brain development trajectories akin to growth curves, (2) characterize reliable metrics for distinguishing illness, and (3) develop clinically useful tools to assist in the diagnosis and management of mental health and learning disorders have gained significant momentum. To this end, the NKI-Rockland Sample initiative was created to probe lifespan development as a large-scale multimodal dataset. The NKI-Rockland Sample Longitudinal Discovery of Brain Development Trajectories substudy (N = 369) is a 24- to 30-month multi-cohort longitudinal pediatric investigation (ages 6.0-17.0 at enrollment) carried out in a community-ascertained sample. Data include psychiatric diagnostic, medical, behavioral, and cognitive phenotyping, as well as multimodal brain imaging (resting fMRI, diffusion MRI, morphometric MRI, arterial spin labeling), genetics, and actigraphy. Herein, we present the rationale, design, and implementation of the Longitudinal Discovery of Brain Development Trajectories protocol.

Indexed as

BrainConnectomeMental HealthAdolescentChildDiffusion Magnetic Resonance ImagingHumans

Identifiers

PMID35701428
PMCPMC9197863
OpenAlexW4282842143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.