Evidence map›Paper›PMID 35701399›Full record

ArticleScientific data2022

Enhancing the REMBRANDT MRI collection with expert segmentation labels and quantitative radiomic features.

Anousheh Sayah, Camelia Bencheqroun, Krithika Bhuvaneshwar, Anas Belouali, Spyridon Bakas, Chiharu Sako, Christos Davatzikos, Adil Alaoui, Subha Madhavan, Yuriy Gusev

Erratum issuedAbstract readDataset
In one paragraph

Article in Scientific data, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Anousheh Sayah *Medstar Georgetown University Hospital, Washington, DC, USA.
Camelia Bencheqroun *Innovation Center for Biomedical Informatics (ICBI), Georgetown University, Washington, DC, USA.
Krithika BhuvaneshwarInnovation Center for Biomedical Informatics (ICBI), Georgetown University, Washington, DC, USA. kb472@georgetown.edu.ORCID http://orcid.org/0000-0003-4015-7056
Anas BeloualiInnovation Center for Biomedical Informatics (ICBI), Georgetown University, Washington, DC, USA.ORCID http://orcid.org/0000-0002-2780-2500
Spyridon BakasCenter for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0001-8734-6482
Chiharu SakoCenter for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0003-3243-3954
Christos DavatzikosCenter for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0002-1025-8561
Adil AlaouiInnovation Center for Biomedical Informatics (ICBI), Georgetown University, Washington, DC, USA.
Subha MadhavanInnovation Center for Biomedical Informatics (ICBI), Georgetown University, Washington, DC, USA.
Yuriy GusevInnovation Center for Biomedical Informatics (ICBI), Georgetown University, Washington, DC, USA. yg63@georgetown.edu.ORCID http://orcid.org/0000-0001-7371-4715

Funding

Tissue Culture Shared ResourceP30CA051008 · NCI · GEORGETOWN UNIVERSITY · PI Louis M Weiner · 1990 to 2026
$71.5M
Maternal Morbidity and Mortality: Risk Factors, Early Detection and Personalized InterventionUL1TR001409 · NCATS · GEORGETOWN UNIVERSITY · PI GONDRE-LEWIS, MARJORIE C, MELLMAN, THOMAS A · 2015 to 2024
$37.8M
Statistical atlases of brain tumor MRI:do imaging phenotypes predict progression?R01NS042645 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS · 2002 to 2024
$8.7M
Cancer imaging phenomics software suite: application to brain and breast cancerU24CA189523 · NCI · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS, KONTOS, DESPINA · 2015 to 2019
$3.2M
Biomedical Image Computing and Informatics ClusterS10OD023495 · OD · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS · 2017 to 2017
$1.9M
The Federated Tumor Segmentation (FeTS) platform: An intuitive tool facilitating secure multi-institutional collaborationU01CA242871 · NCI · UNIVERSITY OF PENNSYLVANIA · PI BAKAS, SPYRIDON · 2019 to 2021
$1.1M
NCATS NIH HHS UL1 TR001409NCI NIH HHS P30 CA051008NCI NIH HHS U01 CA242871NCI NIH HHS U24 CA189523NIH HHS S10 OD023495NINDS NIH HHS R01 NS042645
6 · The paper itself

Abstract

Malignancy of the brain and CNS is unfortunately a common diagnosis. A large subset of these lesions tends to be high grade tumors which portend poor prognoses and low survival rates, and are estimated to be the tenth leading cause of death worldwide. The complex nature of the brain tissue environment in which these lesions arise offers a rich opportunity for translational research. Magnetic Resonance Imaging (MRI) can provide a comprehensive view of the abnormal regions in the brain, therefore, its applications in the translational brain cancer research is considered essential for the diagnosis and monitoring of disease. Recent years has seen rapid growth in the field of radiogenomics, especially in cancer, and scientists have been able to successfully integrate the quantitative data extracted from medical images (also known as radiomics) with genomics to answer new and clinically relevant questions. In this paper, we took raw MRI scans from the REMBRANDT data collection from public domain, and performed volumetric segmentation to identify subregions of the brain. Radiomic features were then extracted to represent the MRIs in a quantitative yet summarized format. This resulting dataset now enables further biomedical and integrative data analysis, and is being made public via the NeuroImaging Tools & Resources Collaboratory (NITRC) repository ( https://www.nitrc.org/projects/rembrandt_brain/ ).

Indexed as

Brain NeoplasmsMagnetic Resonance ImagingBrainGenomicsHumansNeuroimaging

Identifiers

PMID35701399
PMCPMC9198015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.