Evidence map›Paper›PMID 35701162›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2022

Resting-State fMRI-Based Screening of Deschloroclozapine in Rhesus Macaques Predicts Dosage-Dependent Behavioral Effects.

Atsushi Fujimoto, Catherine Elorette, J Megan Fredericks, Satoka H Fujimoto, Lazar Fleysher, Peter H Rudebeck, Brian E Russ

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  9. Chemogenetic Disruption of Monkey Perirhinal Neurons Projecting to the Rostromedial Caudate Impairs Associative Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  10. Article
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  13. What can neuroimaging of neuromodulation reveal about the basis of circuit therapies for psychiatry?Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Review
  14. Article
  15. Article
  16. Evolutionarily conserved neural responses to affective touch in monkeys transcend consciousness and change with age.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  17. Article
  18. Imaging-based chemogenetics for dissecting neural circuits in nonhuman primates.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2024
    Review
  19. Multimodal Imaging for Validation and Optimization of Ion Channel-Based Chemogenetics in Nonhuman Primates.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Atsushi FujimotoNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029.
Catherine EloretteNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029.ORCID https://orcid.org/0000-0001-5735-4369
J Megan FredericksNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029.
Satoka H FujimotoNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029.
Lazar FleysherBioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029.
Peter H RudebeckNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029.ORCID https://orcid.org/0000-0002-1411-7555
Brian E RussNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029 brian.russ@mssm.edu.
Allen Institute for Brain Science · USIcahn School of Medicine at Mount Sinai · USNathan Kline Institute for Psychiatric Research · US

Funding

Defining Neuronal Circuits and Cellular Processes Underlying Resting fMRI SignalsR01MH111439 · NIMH · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · PI MILHAM, MICHAEL PETER, SCHROEDER, CHARLES E · 2016 to 2020
$5.1M
Investigating the molecular, cellular and circuit effects of transcranial magnetic stimulationR01NS109498 · NINDS · UNIVERSITY OF MINNESOTA · PI FALCHIER, ARNAUD Y, OPITZ, ALEXANDER · 2019 to 2022
$3.2M
Mechanistic and causal basis of fMRI functional connectivity in non-human primatesRF1MH117040 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI RUDEBECK, PETER, RUSS, BRIAN E · 2018 to 2018
$2.8M
A new approach to the role of prefrontal-limbic circuits in anxiety disordersR01MH110822 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI RUDEBECK, PETER · 2016 to 2020
$2.2M
NIMH NIH HHS R01 MH110822NIMH NIH HHS R01 MH111439NIMH NIH HHS RF1 MH117040NINDS NIH HHS R01 NS109498
6 · The paper itself

Abstract

Chemogenetic techniques, such as designer receptors exclusively activated by designer drugs (DREADDs), enable transient, reversible, and minimally invasive manipulation of neural activity

Indexed as

Designer DrugsMagnetic Resonance ImagingAnimalsBrainBrain MappingFemaleHumansMacaca mulattaMaleDesigner DrugsdeschloroclozapineDREADDsfunctional connectivityICAmacaque monkeyrs-fMRI

Identifiers

PMID35701162
PMCPMC9302458
OpenAlexW4282943841

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.