Evidence map›Paper›PMID 35701133›Full record

ArticleBeijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences2022

[Analysis of clinical features and risk factors of necrotizing pneumonia in children].

J Qian, Y J Wei, Y J Cheng, Y Zhang, B Peng, C M Zhu

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

J QianDepartment of Respiratory Medicine, Children's Hospital Affiliated to Capital Institute of Pediatrics, National Key Clinical Specialty, Beijing 100020, China.
Y J WeiDepartment of Respiratory Medicine, Children's Hospital Affiliated to Capital Institute of Pediatrics, National Key Clinical Specialty, Beijing 100020, China.
Y J ChengBig Data Center of Capital Institute of Pediatrics, Beijing 100020, China.
Y ZhangDepartment of Respiratory Medicine, Children's Hospital Affiliated to Capital Institute of Pediatrics, National Key Clinical Specialty, Beijing 100020, China.
B PengDepartment of Respiratory Medicine, Children's Hospital Affiliated to Capital Institute of Pediatrics, National Key Clinical Specialty, Beijing 100020, China.
C M ZhuDepartment of Respiratory Medicine, Children's Hospital Affiliated to Capital Institute of Pediatrics, National Key Clinical Specialty, Beijing 100020, China.
Capital Institute of Pediatrics · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the clinical characteristics and risk factor analysis of necrotizing pneumonia in children.

methodsA retrospective study was used to analyze the case data of 218 children with severe pneumonia hospitalized in the Department of Respiratory Medicine, Children's Hospital of Capital Institute of Pediatrics from January 2016 to January 2020, and they were divided into 96 cases in the necrotizing pneumonia group (NP group) and 122 cases in the non-necrotizing pneumonia group (NNP group) according to whether necrosis of the lung occurred. The differences in clinical characteristics (malnutrition, fever duration, hospitalization time, imaging performance, treatment and regression follow-up), laboratory tests [leukocytes, neutrophil ratio, platelet (PLT), C-reactive protein (CRP), procalcitonin (PCT), D-dimer, and lactate dehydrogenase (LDH)] and bronchoscopic performance between the two groups were compared, and Logistic regression analysis of clinical risk factors associated with necrotizing pneumonia was performed to further determine the maximum diagnostic value of each index by subject operating characteristic curve (ROC). The critical value of each index was further determined by the ROC.

resultsThe differences in age, gender, pathogenic classification, and bronchoscopic presentation between the two groups of children were not statistically significant (

conclusionChildren with necrotizing pneumonia have a longer heat course and hospital stay, and the imaging uptake time of mixed pathogenic infections is significantly longer than that of single pathogenic infections. Children with necrotizing pneumonia under 6 years of age have more advantageous efficacy of electronic bronchoscopic alveolar lavage within 10 d of disease duration compared with children in the group over 6 years of age and children in the group with disease duration >10 d. Inflammatory indexes CRP, PCT, and D-dimer are significantly higher. The heat course, CRP, PCT, and D-dimer are risk factors for secondary lung necrosis in severe pneumonia. Heat course >11.5 d, CRP >48.35 mg/L, and D-dimer >4.25 mg/L have high predictive value for the diagnosis of necrotizing pneumonia.

Indexed as

MalnutritionPneumoniaPneumonia, NecrotizingChildChild, PreschoolC-Reactive ProteinHumansNecrosisPrognosisRetrospective StudiesRisk FactorsROC CurveC-Reactive ProteinChildNecrotizing pneumoniaRisk factors

Identifiers

PMID35701133
PMCPMC9197706
OpenAlexW4282976296

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.