Evidence map›Paper›PMID 35701116›Full record

ArticleBeijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences2022

[Interaction between ischemic stroke risk loci identified by genome-wide association studies and sleep habits].

R T Yang, M Y Wang, C N Li, H Yu, X W Wang, J H Wu, S Y Wang, J T Wang, D F Chen, T Wu and 1 more

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

R T YangDepartment of epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
M Y WangDepartment of epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
C N LiDepartment of epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
H YuDepartment of epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
X W WangDepartment of epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
J H WuDepartment of epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
S Y WangDepartment of epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
J T WangDepartment of epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
D F ChenDepartment of epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
T WuDepartment of epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
Y H HuDepartment of epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
Peking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the relationship between sleep habits (sleep duration, sleep efficiency, sleep onset timing) and ischemic stroke, and whether there is an interaction between sleep habits and ischemic stroke susceptibility gene loci.

methodsA questionnaire survey, physical examination, blood biochemical testing and genotyping were conducted among rural residents in Beijing, and the gene loci of ischemic stroke suggested by previous genome-wide association studies (GWAS) were screened. Multivariable generalized linear model was used to analyze the correlation between sleep habits, sleep-gene interaction and ischemic stroke.

resultsA total of 4 648 subjects with an average age of (58.5±8.7) years were enrolled, including 1 316 patients with ischemic stroke. Compared with non-stroke patients, stroke patients with sleep duration ≥9 hours, sleep efficiency < 80%, and sleep onset timing earlier than 22:00 accounted for a higher proportion (

conclusionDecreased sleep efficiency is associated with increased risk of ischemic stroke, and falling asleep earlier than 22:00 is associated with higher risk of ischemic stroke. Sleep onset timing interacted with rs579459 in

Indexed as

Ischemic StrokeStrokeAgedGenome-Wide Association StudyHumansMiddle AgedSleepSurveys and QuestionnairesGene lociInteractionIschemic strokeSleep

Identifiers

PMID35701116
PMCPMC9197694
OpenAlexW4282976021

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.