Evidence map›Paper›PMID 35700955›Full record

ArticleBioorganic & medicinal chemistry letters2022

Synthesis and evaluation of Diaza-Crown Ether-Backboned chelator containing hydroxamate groups for Zr-89 chelation chemistry.

Shuyuan Zhang, Haixing Wang, Siyuan Ren, Yanda Chen, Dijie Liu, Mengshi Li, Edwin Sagastume, Hyun-Soon Chong

Abstract read
In one paragraph

Article in Bioorganic & medicinal chemistry letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. The Evaluation of (1Molecules (Basel, Switzerland) · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shuyuan ZhangDepartment of Chemistry, Illinois Institute of Technology, Chicago, IL, USA.
Haixing WangDepartment of Chemistry, Illinois Institute of Technology, Chicago, IL, USA.
Siyuan RenDepartment of Chemistry, Illinois Institute of Technology, Chicago, IL, USA.
Yanda ChenDepartment of Chemistry, Illinois Institute of Technology, Chicago, IL, USA.
Dijie LiuDepartment of Radiology, University of Iowa, Iowa City, IA, USA; Viewpoint Molecular Targeting Inc, Coralville, IA, USA.
Mengshi LiDepartment of Radiology, University of Iowa, Iowa City, IA, USA; Viewpoint Molecular Targeting Inc, Coralville, IA, USA.
Edwin SagastumeViewpoint Molecular Targeting Inc, Coralville, IA, USA.
Hyun-Soon ChongDepartment of Chemistry, Illinois Institute of Technology, Chicago, IL, USA. Electronic address: Chong@iit.edu.

Funding

XRAY CRYSTALLOGRAPHIC STRUCTURE ANALYSIS: PROTEIN SORTINGP41RR001081 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 1985 to 2011
$17.6M
New Bifunctional Ligands for RadioimmunotherapyR01CA112503 · NCI · ILLINOIS INSTITUTE OF TECHNOLOGY · PI CHONG, HYUN-SOON · 2006 to 2017
$2.0M
Development of Superior Chelation Chemistry for 89Zr-ImmunoPET ImagingR01EB029800 · NIBIB · ILLINOIS INSTITUTE OF TECHNOLOGY · PI CHONG, HYUN-SOON · 2020 to 2021
$790k
NCI NIH HHS R01 CA112503NCRR NIH HHS P41 RR001081NIBIB NIH HHS R01 EB029800
6 · The paper itself

Abstract

Zirconium-89 (

Indexed as

Chelating AgentsCrown EthersAnimalsButylated HydroxyanisoleEdetic AcidHumansHydroxamic AcidsMicePositron-Emission TomographyRadioisotopesZirconiumButylated HydroxyanisoleChelating AgentsCrown EthersEdetic AcidHydroxamic AcidsRadioisotopesZirconiumZirconium-89ChelatorPET ImagingZr-89

Identifiers

PMID35700955
PMCPMC9308756

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.