Evidence map›Paper›PMID 35700803›Full record

ArticleThe Annals of thoracic surgery2022

Systematic Mapping of Conduction Tissue Regions During Congenital Heart Surgery.

Aditya K Kaza, Robert Hitchcock, Abhijit Mondal, Stephanie Tuttle, Brian Cottle, Frank B Sachse, OPTIMA Trial Investigators

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Annals of thoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Aditya K KazaDepartment of Cardiac Surgery, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address: aditya.kaza@cardio.chboston.org.
Robert HitchcockDepartment of Biomedical Engineering, University of Utah, Salt Lake City, Utah.
Abhijit MondalDepartment of Cardiac Surgery, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts.
Stephanie TuttleDepartment of Cardiac Surgery, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts.
Brian CottleDepartment of Biomedical Engineering, University of Utah, Salt Lake City, Utah; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah.
Frank B SachseDepartment of Biomedical Engineering, University of Utah, Salt Lake City, Utah; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah.
OPTIMA Trial Investigators
University of Utah · USHarvard University · USBoston Children's Hospital · US

Funding

Evaluation of Fiberoptic Confocal Microscopy for Pediatric Cardiac SurgeryR01HL135077 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI HITCHCOCK, ROBERT, KAZA, ADITYA K · 2017 to 2020
$2.0M
Evaluation of Fiberoptic Confocal Microscopy for Pediatric Cardiac SurgeryR56HL128813 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI HITCHCOCK, ROBERT, KAZA, ADITYA K · 2016 to 2016
$620k
Interoperative Cardiac Tissue Imaging: Implications in Congenital Heart DiseaseR13HL160044 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI HITCHCOCK, ROBERT, KAZA, ADITYA K · 2021 to 2021
$10k
NHLBI NIH HHS R01 HL135077NHLBI NIH HHS R13 HL160044NHLBI NIH HHS R56 HL128813
6 · The paper itself

Abstract

purposeDamage to the cardiac conduction system is a major risk of congenital cardiac surgery. Localization of the conduction system is commonly based on anatomic landmarks, which are variable in congenital heart diseases. We introduce a novel technique for identification of conduction tissue regions based on real-time fiberoptic confocal microscopy. DESCRIPTION: We developed a fiberoptic confocal microscopy-based technique to document conduction tissue regions and deployed it in pediatric patients undergoing repair of common congenital heart defects. The technique applies clockface schematics for intraoperative documentation of the location of conduction tissue regions. EVALUATION: We created clockface schematics for 11 patients with ventricular septal defects, 6 with tetralogy of Fallot, and 10 with atrioventricular canal defects. The approach revealed substantial variability in the location of the conduction system in hearts with congenital defects. The clockface schematics were used to create plans for subsequent surgical repair.

conclusionsThe clockface schematic provides a reliable fiducial system to document and communicate variability of conduction tissue regions in the heart and applies this information for decision-making during congenital cardiac surgery.

Indexed as

Cardiac Surgical ProceduresHeart Defects, CongenitalHeart Septal DefectsHeart Septal Defects, VentricularTetralogy of FallotChildHumans

Identifiers

PMID35700803
PMCPMC9903201
OpenAlexW4282959922

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.