Evidence map›Paper›PMID 35700455›Full record

ReviewHuman vaccines & immunotherapeutics2022

Acute encephalitis after COVID-19 vaccination: A case report and literature review.

Jhih-Jian Gao, Hung-Pin Tseng, Chun-Liang Lin, Ruei-Fong Hsu, Ming-Hsun Lee, Ching-Hsiung Liu

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Human vaccines & immunotherapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Neurological Adverse Reactions to SARS-CoV-2 Vaccines.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2023
    Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Neurologia (Barcelona, Spain) · 2022
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jhih-Jian GaoDepartment of Neurology, Lotung Poh-Ai Hospital, Ilan, Taiwan.ORCID 0000-0003-3981-3028
Hung-Pin TsengDepartment of Neurology, Lotung Poh-Ai Hospital, Ilan, Taiwan.
Chun-Liang LinDepartment of Neurology, Lotung Poh-Ai Hospital, Ilan, Taiwan.
Ruei-Fong HsuDepartment of Emergency Medicine, Lotung Poh-Ai Hospital, Ilan, Taiwan.
Ming-Hsun LeeDepartment of Radiology, Lotung Poh-Ai Hospital, Ilan, Taiwan.
Ching-Hsiung LiuDepartment of Neurology, Lotung Poh-Ai Hospital, Ilan, Taiwan.ORCID 0000-0002-1174-473X
Luodong Poh-Ai Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccine-related immune responses are one of the causes of encephalitis. Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) have been administered worldwide due to the ongoing global pandemic; cases of SARS-CoV-2 vaccination-related encephalitis were scarcely reported. An 82-year-old female was diagnosed with acute encephalitis following her first dose of vaccination with mRNA-1273 against SARS-CoV-2. The patient presented with fever and headache five days after vaccination, followed by behavior change 17 days after vaccination. Electroencephalographic recordings revealed focal slow waves in the right frontoparietal regions. Brain MRI revealed the signal change in the right middle and posterior temporal lobe. Cerebrospinal fluid analysis showed mildly elevated protein. She responded well to steroid pulse therapy and made a full recovery. The severity of the immune response following COVID-19 vaccination may be alleviated if adequate treatment is achieved. Physicians must be alert for encephalitis after vaccination to help ensure a favorable outcome.

Indexed as

2019-nCoV Vaccine mRNA-1273COVID-19EncephalitisAged, 80 and overFemaleHumansSARS-CoV-2Vaccination2019-nCoV Vaccine mRNA-1273COVID-19encephalitisneurological complicationsSARS-COV-2vaccination

Identifiers

PMID35700455
PMCPMC9621012
OpenAlexW4282938112

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.