Evidence map›Paper›PMID 35700402›Full record

ArticleMolecular pharmaceutics2022

Investigation of Copper-64-Based Host-Guest Chemistry Pretargeted Positron Emission Tomography.

Vilma I J Jallinoja, Brandon D Carney, Kavita Bhatt, Courtney H Abbriano, David J Schlyer, Paul J Yazaki, Jacob L Houghton

Open access · greenAbstract read
In one paragraph

Article in Molecular pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Pretargeting with Cucurbituril-Adamantane Host-Guest Pair in Xenograft Models.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  4. Recent Advances inInternational journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Vilma I J JallinojaDepartment of Radiology, Stony Brook University, Stony Brook, New York 11794, United States.ORCID 0000-0001-5857-6684
Brandon D CarneyDepartment of Radiology, Stony Brook University, Stony Brook, New York 11794, United States.
Kavita BhattDepartment of Radiology, Stony Brook University, Stony Brook, New York 11794, United States.
Courtney H AbbrianoDepartment of Radiology, Stony Brook University, Stony Brook, New York 11794, United States.
David J SchlyerDepartment of Radiology, Stony Brook University, Stony Brook, New York 11794, United States.
Paul J YazakiBeckman Institute, City of Hope, Duarte, California 91010, United States.
Jacob L HoughtonDepartment of Radiology, Stony Brook University, Stony Brook, New York 11794, United States.ORCID 0000-0003-4255-3044
Stony Brook University · USBrookhaven National Laboratory · USCity Of Hope National Medical Center · USVanderbilt University · US

Funding

Postdoctoral Training in Biomedical MRI and MRST32EB001628 · NIBIB · VANDERBILT UNIVERSITY MEDICAL CENTER · PI John C Gore · 2003 to 2026
$7.0M
Development and Validation of a Robust and Modular Host: Guest-based Pretargeting PlatformR21EB027982 · NIBIB · STATE UNIVERSITY NEW YORK STONY BROOK · PI HOUGHTON, JACOB · 2020 to 2022
$638k
Acquisition of an Applied Biosystems 4000 QTRAP Mass SpectrometerS10RR023680 · NCRR · STATE UNIVERSITY NEW YORK STONY BROOK · PI IDEN, CHARLES R · 2007 to 2007
$435k
NCRR NIH HHS S10 RR023680NIBIB NIH HHS R21 EB027982NIBIB NIH HHS T32 EB001628
6 · The paper itself

Abstract

Pretargeting is a technique that uses macromolecules as targeting agents for nuclear imaging and therapy with the goal of reducing the radiation toxicity to healthy tissues often associated with directly radiolabeled macromolecules. In pretargeting, a macromolecule is radiolabeled

Indexed as

Copper RadioisotopesImmunoconjugatesAnimalsAntibodies, MonoclonalCell Line, TumorHumansMetallocenesMicePositron-Emission TomographyAntibodies, MonoclonalCopper RadioisotopesImmunoconjugatesMetallocenescarcinoembryonic antigencopper-64host-guest chemistrypositron emission tomographypretargeting

Identifiers

PMID35700402
PMCPMC11271262
OpenAlexW4282916094

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.