Evidence map›Paper›PMID 35700139›Full record

ReviewJournal of clinical microbiology2022

Time for Some Group Therapy: Update on Identification, Antimicrobial Resistance, Taxonomy, and Clinical Significance of the Bacteroides fragilis Group.

Sophonie Jean, Miranda J Wallace, Gautam Dantas, Carey-Ann D Burnham

Open access · greenAbstract readReview
In one paragraph

Review in Journal of clinical microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 46 citations in OpenAlex.

  1. Trial
  2. Diverse Genomic Mechanisms ofAntibiotics (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Animals : an open access journal from MDPI · 2025
    Article
  8. The Emergence ofMicroorganisms · 2025
    Review
  9. Article
  10. Article
  11. Clinical Outcomes and Molecular Characteristics ofAnnals of laboratory medicine · 2025
    Article
  12. Article
  13. Megaprosthesis Infection byClinical case reports · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sophonie Jean *Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.ORCID 0000-0001-9372-3491
Miranda J Wallace *Department of Pathology & Immunology, Division of Laboratory and Genomic Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0003-3036-4545
Gautam DantasDepartment of Pathology & Immunology, Division of Laboratory and Genomic Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0003-0455-8370
Carey-Ann D BurnhamDepartment of Pathology & Immunology, Division of Laboratory and Genomic Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0002-1137-840X
Washington University in St. Louis · USNationwide Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteroides fragilis group (BFG) species are common members of the human microbiota that provide several benefits to healthy hosts, yet BFG are also the most common anaerobes isolated from human infections, including intra-abdominal infections, abscesses, and bloodstream infection. Compared to many other anaerobes associated with disease, members of the BFG are more likely to be resistant to commonly used antimicrobials, including penicillin (>90% resistant), carbapenems (2 to 20% resistant), and metronidazole (0.2 to 4% resistant). As a result, infection with BFG bacteria can be associated with poor clinical outcomes. Here, we discuss the role of BFG in human health and disease, proposed taxonomic reclassifications within the BFG, and updates in methods for species-level identification. The increasing availability of whole-genome sequencing (WGS) supports recent proposals that the BFG now span two families (

Indexed as

Bacteroides fragilisPsychotherapy, GroupAgarAnti-Bacterial AgentsBacteria, AnaerobicBacteroidesCarbapenemsDrug Resistance, BacterialHumansMetronidazoleMicrobial Sensitivity TestsPenicillinsSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationAgarAnti-Bacterial AgentsCarbapenemsMetronidazolePenicillinsantibiotic resistanceantimicrobial agentsBacteroidesMALDI-TOF MSParabacteroidesPhocaeicolataxonomywhole-genome sequencing

Identifiers

PMID35700139
PMCPMC9491163
OpenAlexW4282824389

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.