Evidence map›Paper›PMID 35700135›Full record

ArticleMicrobiology spectrum2022

AI-2/LuxS Quorum Sensing System Promotes Biofilm Formation of Lactobacillus rhamnosus GG and Enhances the Resistance to Enterotoxigenic Escherichia coli in Germ-Free Zebrafish.

Zhaoxi Deng, Kangwei Hou, Teresa G Valencak, Xin M Luo, Jianxin Liu, Haifeng Wang

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
6.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 69 citations in OpenAlex.

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  10. Effect ofAmerican journal of translational research · 2026
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  15. DietaryInternational journal of molecular sciences · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Zhaoxi DengCollege of Animal Science, MOE Key Laboratory of Molecular Animal Nutrition, Zhejiang Universitygrid.13402.34, Hangzhou, P.R. China.
Kangwei HouCollege of Animal Science, MOE Key Laboratory of Molecular Animal Nutrition, Zhejiang Universitygrid.13402.34, Hangzhou, P.R. China.
Teresa G ValencakCollege of Animal Science, MOE Key Laboratory of Molecular Animal Nutrition, Zhejiang Universitygrid.13402.34, Hangzhou, P.R. China.
Xin M LuoDepartment of Biomedical Sciences and Pathobiology, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.ORCID 0000-0002-2809-5836
Jianxin LiuCollege of Animal Science, MOE Key Laboratory of Molecular Animal Nutrition, Zhejiang Universitygrid.13402.34, Hangzhou, P.R. China.ORCID 0000-0002-5812-5186
Haifeng WangCollege of Animal Science, MOE Key Laboratory of Molecular Animal Nutrition, Zhejiang Universitygrid.13402.34, Hangzhou, P.R. China.ORCID 0000-0002-8211-9691
Zhejiang University · CNVirginia Tech · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The LuxS enzyme plays a key role in both quorum sensing (QS) and the regulation of bacterial growth. It catalyzes the production of autoinducer-2 (AI-2) signaling molecule, which is a component of the methyl cycle and methionine metabolism. This study aimed at investigating the differences between the Lactobacillus rhamnosus GG (LGG) wild-type strain (WT) and its

Indexed as

Enterotoxigenic Escherichia coliLacticaseibacillus rhamnosusAnimalsBacterial ProteinsBiofilmsCarbon-Sulfur LyasesGene Expression Regulation, BacterialInflammationQuorum SensingZebrafishBacterial ProteinsCarbon-Sulfur Lyasesanti-inflammatorybiofilmLactobacillus rhamnosus GGluxS mutantquorum sensingzebrafish

Identifiers

PMID35700135
PMCPMC9430243
OpenAlexW4282915960

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.