Evidence map›Paper›PMID 35700027›Full record

ArticleJournal of the International AIDS Society2022

Improving ART initiation among men who use HIV self-testing in Malawi: a qualitative study.

Julie A Hubbard, Misheck Mphande, Khumbo Phiri, Kelvin Balakasi, Risa M Hoffman, Joseph Daniels, Augustine Choko, Thomas J Coates, Kathryn Dovel

Open access · goldAbstract read
In one paragraph

Article in Journal of the International AIDS Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Julie A HubbardDivision of Infectious Diseases, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.ORCID 0000-0002-5704-6822
Misheck MphandePartners in Hope Medical Center, Lilongwe, Malawi.
Khumbo PhiriPartners in Hope Medical Center, Lilongwe, Malawi.
Kelvin BalakasiPartners in Hope Medical Center, Lilongwe, Malawi.
Risa M HoffmanDivision of Infectious Diseases, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.ORCID 0000-0001-9575-4574
Joseph DanielsEdson College of Nursing and Health Innovation, Arizona State University, Phoenix, Arizona, USA.
Augustine ChokoMalawi-Liverpool-Wellcome Trust Clinical Research Programme, TB/HIV, Blantyre, Malawi.ORCID 0000-0001-6095-9430
Thomas J CoatesDivision of Infectious Diseases, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.
Kathryn DovelDivision of Infectious Diseases, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.ORCID 0000-0002-5622-3401
Partners In Health · USUniversity of California, Los Angeles · USArizona State University · USUniversity of Liverpool · GB

Funding

UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Sung-Jae Lee · 1997 to 2026
$53.5M
Engaging men through HIV self-test and differentiated care models to increase ART initiation and viral suppression in MalawiR01MH122308 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DOVEL, KATHRYN L · 2020 to 2024
$2.7M
Innovative strategies to increase ART Initiation and viral suppression among HIV+ men in MalawiK01TW011484 · FIC · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DOVEL, KATHRYN L · 2019 to 2023
$717k
FIC NIH HHS K01 TW011484NIMH NIH HHS P30 MH058107NIMH NIH HHS R01 MH122308
6 · The paper itself

Abstract

introductionHIV self-testing (HIVST) increases HIV testing uptake among men; however, the linkage to antiretroviral therapy (ART) among HIVST users is low. Innovative strategies for ART initiation are needed, yet little is known about the unique barriers to care experienced by male HIVST users, and what ART-related interventions men desire.

methodsWe conducted semi-structured in-depth interviews with cisgender men (≥15 years) in Malawi who tested HIV positive using HIVST between 2018 and 2020, as well as interviews with their female partners (≥15 years) who distributed the HIVST kits. Medical records from seven facilities were used to identify respondents. We included men who received HIVST from a health facility (primary distribution) and from sexual partners (secondary distribution). Interview guides focused on unique barriers to ART initiation following HIVST and desired interventions to improve linkage and initiation. Interviews were audio recorded, translated and transcribed to English, and analysed using constant comparison methods in Atlas.ti v.8.4. Themes were compared by HIVST distribution strategy. Data were collected between 2019 and 2020.

resultsTwenty-seven respondents were interviewed: eight male/female dyads (16 respondents), eight men without a female partner and three women who represented men who did not participate in the study. Among the 19 men represented (16 men interviewed in person, three represented by secondary report from female partners), seven received HIVST through primary distribution, 12 through secondary distribution. Six men never initiated ART (all secondary HIVST distribution). Barriers to ART initiation centred on the absence of healthcare workers at the time of diagnosis and included lack of external motivation for linkage to care (men had to motivate themselves) and lack of counselling before and after testing (leaving ART-related fears and misconceptions unaddressed)--the latter was especially true for secondary HIVST distribution. Desired interventions were similar across distribution strategies and included ongoing peer mentorship for normalizing treatment adherence, counselling messages tailored to men, outside-facility services for convenience and privacy, and facility navigation to help men understand how to navigate ART clinics.

conclusionsMale HIVST users face unique challenges to ART initiation, especially those receiving HIVST through secondary distribution. Male-tailored interventions are desired by men and may help overcome barriers to care.

Indexed as

HIV InfectionsFemaleHIV TestingHumansMalawiMaleMass ScreeningSelf-TestingSexual Partnersantiretroviral therapyhighly activemenqualitative researchself-testingsub-Saharan Africa

Identifiers

PMID35700027
PMCPMC9196890
OpenAlexW4282832005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.