Evidence map›Paper›PMID 35699591›Full record

ArticleNuclear medicine review. Central & Eastern Europe2022

Radiopharmaceutical for detecting PSMA - positive metastatic colon cancer: Matched-pair comparison of 18F-BF3-Cy3-ACUPA and 68Ga-PSMA PET/MRI.

Omer Aras, Cetin Demirdag, Harikrishna Kommidi, Richard Ting, Haluk B Sayman

Open access · diamondAbstract read
In one paragraph

Article in Nuclear medicine review. Central & Eastern Europe, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. PSMA expression in hepatic colorectal cancer metastasis.Journal of pathology and translational medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Omer ArasDepartament of Radiology, Memorial Sloan Kettering Cancer Center, New York, United States. dromeraras@gmail.com.ORCID 0000-0003-1758-0542
Cetin DemirdagDepartment of Urology, Cerrahpasa Medical Faculty, Istanbul, Turkey.ORCID 0000-0002-8912-9155
Harikrishna KommidiDepartment of Radiology, Weill Cornell Medicine, New York, United States.ORCID 0000-0002-4428-5576
Richard TingDepartment of Radiology, Weill Cornell Medicine, New York, United States.ORCID 0000-0003-2096-5232
Haluk B SaymanDepartment of Nuclear Medicine, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul,Turkey.ORCID 0000-0002-0954-5707
Cornell University · USIstanbul University-Cerrahpaşa · TRMemorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Prostate-specific membrane antigen (PSMA) - based radiopharmaceuticals are promising for the evaluation of PSMA-positive non-prostate cancers. In this case study, 18F-BF3-Cy3-ACUPA and 68Ga-PSMA positron emission tomography/magnetic resonance imaging (PET/MRI) were compared in a patient with metastatic colon cancer. Both 18F-BF3-Cy3-ACUPA and 68Ga-PSMA PET/MRI showed biopsy-proven metastatic left external iliac adenopathy, highlighting the feasibility of PSMA uptake in PET/MRI of metastatic nodal disease from colon cancer. Along with imaging evaluation, PSMA-based radiopharmaceuticals may also be used as a surrogate imaging tracer for potential theranostic applications using alpha or beta emitters in the context of PSMA-directed radiopharmaceutical therapy in advanced and progressive colorectal cancer.

Indexed as

Colonic NeoplasmsProstatic NeoplasmsGallium IsotopesGallium RadioisotopesGlutaratesHumansMagnetic Resonance ImagingMalePositron-Emission TomographyPositron Emission Tomography Computed TomographyRadiopharmaceuticalsgallium 68 PSMA-11Gallium IsotopesGallium RadioisotopesGlutaratesRadiopharmaceuticals(S)-2-(3-((S)-5-amino-1-carboxypentyl)ureido)-pentanedioic acid18F-BF3-Cy3-ACUPA68Ga-PSMAcolorectal cancerPET/MRIPSMA

Identifiers

PMID35699591
PMCPMC9878462
OpenAlexW4282825021

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.