Evidence map›Paper›PMID 35698995›Full record

ArticleJournal of natural products2022

Anti-HIV Tigliane-Type Diterpenoids from the Aerial Parts of

Di Zhou, Kouharu Otsuki, Mi Zhang, Gang Chen, Zi-Song Bai, Haotian Yu, Takashi Kikuchi, Li Huang, Chin-Ho Chen, Wei Li and 1 more

Abstract read
In one paragraph

Article in Journal of natural products, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Di ZhouSchool of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang110016, People's Republic of China.
Kouharu OtsukiFaculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba274-8510, Japan.ORCID 0000-0001-6730-0663
Mi ZhangFaculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba274-8510, Japan.
Gang ChenSchool of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang110016, People's Republic of China.ORCID 0000-0002-3152-1269
Zi-Song BaiSchool of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang110016, People's Republic of China.
Haotian YuSchool of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang110016, People's Republic of China.
Takashi KikuchiFaculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba274-8510, Japan.ORCID 0000-0001-8832-5720
Li HuangSurgical Science, Department of Surgery, Duke University Medical Center, Durham, North Carolina27710, United States.
Chin-Ho ChenSurgical Science, Department of Surgery, Duke University Medical Center, Durham, North Carolina27710, United States.ORCID 0000-0001-6880-2104
Wei LiFaculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba274-8510, Japan.ORCID 0000-0003-4143-8597
Ning LiSchool of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang110016, People's Republic of China.ORCID 0000-0001-7410-7327

Funding

New Non-Nuceleotide Reverse Transcriptase Inhibitors for Drug Resistant HIV StrainsR01AI165473 · NIAID · DUKE UNIVERSITY · PI CHEN, CHIN-HO · 2021 to 2023
$1.6M
NIAID NIH HHS R01 AI165473
6 · The paper itself

Abstract

Tigliane-type diterpenoids have attracted much attention in drug discovery since they have been reported to exhibit remarkable biological effects, such as tumor-promoting, antineoplastic, and anti-HIV activities. In continuing our efforts to discover novel biologically important diterpenoids from

Indexed as

DiterpenesPhorbolsWikstroemiaMolecular StructurePlant Components, AerialDiterpenesPhorbols

Identifiers

PMID35698995
PMCPMC9897292

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.