Evidence map›Paper›PMID 35698910›Full record

ArticleClinical and experimental dental research2022

Periapical status in patients affected by osteoporosis: A retrospective clinical study.

Erika Cadoni, Francesca Ideo, Giuseppe Marongiu, Silvia Mezzena, Luca Frigau, Quirico Mela, Antonio Capone, Henry F Duncan, Elisabetta Cotti

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and experimental dental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Erika CadoniDepartment of Conservative Dentistry and Endodontics, University of Cagliari, Cittadella Universitaria di Monserrato, Monserrato, Cagliari, Italy.
Francesca IdeoDepartment of Conservative Dentistry and Endodontics, University of Cagliari, Cittadella Universitaria di Monserrato, Monserrato, Cagliari, Italy.ORCID 0000-0002-7116-0656
Giuseppe MarongiuDepartment of Surgical Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Monserrato, Cagliari, Italy.
Silvia MezzenaDepartment of Conservative Dentistry and Endodontics, University of Cagliari, Cittadella Universitaria di Monserrato, Monserrato, Cagliari, Italy.
Luca FrigauDepartment of Economics and Business Sciences, University of Cagliari, Cagliari, Italy.
Quirico MelaDepartment of Medical Sciences and Public Health, University of Cagliari, Cittadella Universitaria di Monserrato, Monserrato, Cagliari, Italy.
Antonio CaponeDepartment of Surgical Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Monserrato, Cagliari, Italy.
Henry F DuncanDivision of Restorative Dentistry and Periodontology, Dublin Dental University Hospital, Trinity College Dublin, Dublin, Ireland.
Elisabetta CottiDepartment of Conservative Dentistry and Endodontics, University of Cagliari, Cittadella Universitaria di Monserrato, Monserrato, Cagliari, Italy.
University of Cagliari · ITTrinity College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the periapical status in patients with osteoporosis (OP) treated with denosumab (D), bisphosphonates (BPs), or not on medication, and to understand if these conditions influence the prevalence and the progression of apical periodontitis (AP). MATERIAL AND

methodsSeventy-six patients with OP alone or treated with D, or BPs, formed the study group (O), and those from 76 patients matched for age and sex, without diseases, and not taking medications, constituted the control (C) in this retrospective case-control study. The data from the complete clinical and radiographic examination, medical history, decayed, missing, and filled teeth (DMFT), and periapical index score (PAI) were recorded for each patient. Wilcoxon rank test, χ

resultsThe prevalence of AP was similar in O and C. Furthermore, AP was significantly more frequent in root canal-treated teeth in O patients (p = .03).

conclusionsOP does not appear to be associated with the development of AP. Moreover, the increased prevalence of AP in root canal-treated teeth in O patients highlights a possible relationship between the healing dynamics of the disease post-therapy and the patients' medication. A larger sample is needed to confirm these findings.

Indexed as

OsteoporosisPeriapical PeriodontitisCase-Control StudiesDenosumabDiphosphonatesHumansRetrospective StudiesDenosumabDiphosphonatesapical periodontitisbisphosphonatesdenosumabosteoporosis

Identifiers

PMID35698910
PMCPMC9562578
OpenAlexW4282920803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.