ArticleBone & joint open2022
High rate of tibial debonding and failure in a popular knee replacement : a follow-up review.
Article in Bone & joint open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 25 citations in OpenAlex.
- Gait-to-Contact (G2C): A Novel Deep Learning Framework to Predict Total Knee Replacement Wear from Gait Patterns.Annals of biomedical engineering · 2026Article
- Deep learning applied to standard radiographs improves detection of implant loosening in total knee arthroplasty: A proof-of-concept study.Journal of experimental orthopaedics · 2026Article
- Causative factors for varus tibial baseplate subsidence in primary total knee arthroplasty: A retrospective analysis.Journal of orthopaedics · 2025Article
- Wood-Derived Hydrogels for Osteochondral Defect Repair.ACS nano · 2025Article
- Is Wear Still a Concern in Total Knee Arthroplasty With Contemporary Conventional and Highly Crosslinked Polyethylene Tibial Inserts in the mid- to Long-Term?Arthroplasty today · 2024Article
- Short-term survival of the cementless triathlon total knee arthroplasty in a young patient cohort.Archives of orthopaedic and trauma surgery · 2024Article
- Is there an increased revision rate due to early tibial component loosening with a modern total knee arthroplasty design? A retrospective analysis from a large volume arthroplasty centre.Arthroplasty (London, England) · 2024Article
- Does lucency equate to revision? A five-year retrospective review of Attune and Triathlon total knee arthroplasty.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTotal knee arthroplasty (TKA) is a common and safe orthopaedic procedure. Zimmer Biomet's NexGen is the second most popular brand of implant used in the UK. The primary cause of revision after the first year is aseptic loosening. We present our experience of using this implant, with significant concerns around its performance with regards early aseptic loosening of the tibial component.
methodsA retrospective, single-surgeon review was carried out of all of the NexGen Legacy Posterior Stabilized (LPS) TKAs performed in this institute. The specific model used for the index procedures was the NexGen Complete Knee System (Legacy Knee-Posterior Stabilized LPS-Flex Articular Surface, LPS-Flex Femoral Component Option, and Stemmed Nonaugmentable Tibial Component Option).
resultsBetween 2013 and 2016, 352 NexGen TKAs were carried out on 331 patients. A total of 62 TKAs have been revised to date, giving an all-cause revision rate of 17.6% at a minimum of five years. Three of these revisions were due to infection. Overall, 59 of the revisions were performed for aseptic loosening (16.7%) of the tibial component. The tibial component was removed intraoperatively without instrumentation due to significant tibial debonding between the implant-cement interface.
conclusionWhile overall, we believe that early aseptic loosening is multi-factorial in nature, the significantly high aseptic revision rate, as seen by an experienced fellowship-trained arthroplasty surgeon, has led us to believe that there is a fundamental issue with this NexGen implant design. Continued implant surveillance and rigorous review across all regions using this particular implant is warranted based on the concerning findings described here. Cite this article:
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