Evidence map›Paper›PMID 35698727›Full record

ArticleThe Journal of international medical research2022

Fluorescence-guided surgery for osteoradionecrosis of the jaw: a retrospective study.

Suad Aljohani, Riham Fliefel, Teresa Franziska Brunner, Aristeidis Chronopoulos, Nada Binmadi, Sven Otto

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of international medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Suad AljohaniDepartment of Oral Diagnostic Sciences, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia.ORCID https://orcid.org/0000-0002-4169-6046
Riham FliefelDepartment of Oral and Maxillofacial Surgery and Facial Plastic Surgery, Ludwig Maximilians University, Munich, Germany.
Teresa Franziska BrunnerDepartment of Oral and Maxillofacial Surgery and Facial Plastic Surgery, Ludwig Maximilians University, Munich, Germany.
Aristeidis ChronopoulosDepartment of Oral and Maxillofacial Surgery and Facial Plastic Surgery, Ludwig Maximilians University, Munich, Germany.
Nada BinmadiDepartment of Oral Diagnostic Sciences, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia.
Sven OttoDepartment of Oral and Maxillofacial Surgery and Facial Plastic Surgery, Ludwig Maximilians University, Munich, Germany.
Ludwig-Maximilians-Universität München · DEKing Abdulaziz University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveOsteoradionecrosis of the jaw (ORNJ) is one of the most severe head and neck complications in patients treated with radiotherapy. The goal of treatment is to suppress ORNJ progression. Currently, surgical removal of necrotic bone is an effective management approach for advanced stages. In this study, we present our experience in managing ORNJ using fluorescence-guided surgery.

methodsNineteen ORNJ lesions in 15 hospitalized patients were treated with fluorescence-guided surgery. We retrospectively reviewed patients' demographic data, comorbidities, local preceding event, location, ORNJ stage, and treatment outcomes with a median follow-up of 12 months.

resultsTwelve lesions (63%) were treated surgically under tetracycline fluorescence, and seven lesions (37%) were surgically treated under auto-fluorescence. Overall, four lesions (21%) achieved complete mucosal healing, eight lesions (42%) showed partial mucosal healing with bone exposure and no signs or symptoms of inflammation, and seven lesions (37%) were progressive. The results showed that either healing or ORNJ stabilization was achieved in 63% of lesions (n = 12).

conclusionFluorescence-guided surgery can be beneficial in curing or stabilizing ORNJ. However, randomized clinical trials are needed to confirm these findings.

Indexed as

OsteoradionecrosisSurgery, Computer-AssistedComorbidityHumansRetrospective StudiesTreatment Outcomefluorescence-guided surgeryosteonecrosis of the jawOsteoradionecrosisosteoradionecrosis of the jawpatient managementradiotherapy

Identifiers

PMID35698727
PMCPMC9201330
OpenAlexW4282829426

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.