Evidence map›Paper›PMID 35698698›Full record

ArticleCureus2022

A Rare Case of Neuromyelitis Optica Spectrum Disorders With Unknown Fever and Subacute Cognitive Decline With Normal Images.

Kento Furuya, Naoya Itoh

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kento FuruyaDepartment of Emergency, Shizuoka General Hospital, Shizuoka, JPN.
Naoya ItohDivision of Infectious Diseases, Aichi Cancer Center Hospital, Nagoya, JPN.
Aichi Cancer Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a 69-year-old Japanese man who came to our hospital with a chief complaint of fever and cognitive decline for three weeks. There were no neurological abnormalities other than the decreased level of consciousness. He developed urinary retention after admission, so we performed a lumbar puncture, although his head and neck magnetic resonance imaging (MRI) showed no abnormal findings. The cerebrospinal fluid (CSF) examination showed albuminocytologic dissociation and the anti-aquaporin 4 antibody was positive. Thus, we diagnosed him with neuromyelitis optica spectrum disorder (NMOSD). NMOSD is an autoimmune disease that causes demyelination. The clue to diagnosing NMOSD is demyelinating findings on MRI. Therefore, it is difficult to diagnose NMOSD if there are no abnormalities on the images. However, abnormal MRI findings are not necessary for the diagnosis of NMOSD. Thus, NMOSD cannot be ruled out even if MRI findings are normal and the real clue to diagnosing NMOSD is the anti-aquaporin 4 antibody.

Indexed as

altered consciousnessanti-aquaporin 4 antibodyfever of unknown originhashimoto’s encephalopathymagnetic resonance imagingneuromyelitis optica spectrum disorder

Identifiers

PMID35698698
PMCPMC9188466
OpenAlexW4280537567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.