Evidence map›Paper›PMID 35698188›Full record

ArticleWorld journal of surgical oncology2022

Impact of the ACOSOG Z0011 trial on surgical practice in Asian patients: trends in axillary surgery for breast cancer from a Korean Breast Cancer Registry analysis.

Chihwan Cha, Eun Young Kim, Sung Yong Kim, Jai Min Ryu, Min Ho Park, Seokwon Lee, Young-Jin Suh, Nayeon Choi, Hanpyo Hong, Hyung Suk Kim and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of surgical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Breast Cancer Statistics in Korea, 2021.Journal of breast cancer · 2024
    Review
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 1 country.

Chihwan ChaDepartment of Surgery, Hanyang University College of Medicine, 222, Wangsimni-ro, Seongdong-gu, 04764, Seoul, South Korea.
Eun Young KimDepartment of Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Sung Yong KimDepartment of Surgery, Soonchunhyang University Cheonan Hospital, Cheonan, Chungnam, South Korea.
Jai Min RyuDepartment of Surgery, Samsung Comprehensive Cancer Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Min Ho ParkDepartment of Surgery, Chonnam National University Medical School & Hospital, Gwangju, South Korea.
Seokwon LeeDepartment of Surgery, Biomedical Research Institute, Pusan National University Hospital, Busan, South Korea.
Young-Jin SuhDepartment of Surgery, The Catholic University of Korea St. Vincent's Hospital, Suwon, South Korea.
Nayeon ChoiBiostatistical Consulting and Research Lab, Medical Research Collaborating Center, Hanyang University, Seoul, South Korea.
Hanpyo HongBiostatistical Consulting and Research Lab, Medical Research Collaborating Center, Hanyang University, Seoul, South Korea.
Hyung Suk KimDepartment of Surgery, Hanyang University Guri Hospital, Hanyang University College of Medicine, Gyeonggi-do, South Korea.
Min Sung ChungDepartment of Surgery, Hanyang University College of Medicine, 222, Wangsimni-ro, Seongdong-gu, 04764, Seoul, South Korea. bovie@hanyang.ac.kr.ORCID http://orcid.org/0000-0001-5086-3718
Korean Breast Cancer Society
Hanyang University · KRChonnam National University Hospital · KRHanyang University Guri Hospital · KRKangbuk Samsung Hospital · KRPusan National University Hospital · KRSamsung Medical Center · KRSoonchunhyang University · KRThe Catholic University of Korea St. Vincent's Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSince the publication of the Z0011 trial, practice-changing clinical guidelines for breast surgery have been developed. Although recent studies confirmed the feasibility of the Z0011 strategy in Asian populations, there has been no study on the trends of axillary surgery in Asian cohort. This study aimed to investigate the time trend of axillary surgery for breast cancer from a Korean Breast Cancer Registry to understand the impact of the Z0011 trial in Asian patients.

methodsWe collected prospectively constructed data from the nationwide Korean Breast Cancer Registry (KBCR). We identified patients who underwent sentinel node biopsy followed by breast-conserving surgery from 2011 to 2018 and were found to have pathological stage T1-2N1-3M0 disease. Regression analyses were performed to compare the downward trend of axillary lymph node dissection (ALND) in Korean cohort with that previously reported in a Dutch cohort.

resultsFrom KBCR data, 7478 patients met the inclusion criteria. The proportion of ALND significantly decreased from 2011 (76.6%) to 2018 (47.5%). Multivariate analysis revealed that earlier years at diagnosis, larger tumor size, and lymphatic invasion were associated with a higher odds ratio of performing ALND. Compared to the Dutch cohort, the downward trend of ALND in Korea was significantly more gradual (annual percent change: 37.2 vs. 5.8%, p < 0.001).

conclusionsThis study demonstrated a downward trend of ALND in Korean patients with breast cancer. However, the rate of decrease was significantly slower than that in the Dutch cohort.

Indexed as

AxillaBreastBreast NeoplasmsCohort StudiesFemaleHumansLymph Node ExcisionLymph NodesProspective StudiesRegistriesRegression AnalysisRepublic of KoreaSentinel Lymph Node BiopsyBreast cancerSentinel lymph node biopsyTrends

Identifiers

PMID35698188
PMCPMC9195282
OpenAlexW4282567377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.