ArticleBMC cardiovascular disorders2022
Prevalence and prognosis of left ventricular diastolic dysfunction in community hypertension patients.
Article in BMC cardiovascular disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 13 citations in OpenAlex.
- Predictors of echocardiographic abnormalities in asymptomatic individuals with increased cardiothoracic ratio detected on chest radiography.American heart journal plus : cardiology research and practice · 2026Article
- Echocardiographic assessment in arterial hypertension: a contemporary narrative review.Echo research and practice · 2026Review
- Longitudinal Echocardiographic Parameters of Diastolic Dysfunction Are Influenced by Kidney Function: A Study in Routine Clinical Practice.Journal of the American Heart Association · 2026Article
- Association between left ventricle diastolic dysfunction and circadian blood pressure pattern in arterial hypertension.BMC cardiovascular disorders · 2025Article
- T2D-LVDD: neural network-based predictive models for left ventricular diastolic dysfunction in type 2 diabetes.Diabetology & metabolic syndrome · 2025Article
- Cardiorespiratory fitness in stroke patients with different activities of daily living levels: a cross-sectional study.Scientific reports · 2025Article
- Prevalence and Long-Term Prognostic Significance of Advanced Diastolic Dysfunction Among Hospitalized Patients Referred for Echocardiography.Journal of clinical medicine · 2025Article
- Metabolic syndrome, left ventricular diastolic dysfunction and heart failure with preserved ejective fraction.Frontiers in endocrinology · 2025Review
- Interpreting Diastolic Dynamics and Evaluation through Echocardiography.Life (Basel, Switzerland) · 2024Review
- Prognostic nutritional index as a predictor of cardiovascular and all-cause mortality in American adults with hypertension: results from the NHANES database.Frontiers in cardiovascular medicine · 2024Article
- Sex-specific differences and predictors of echocardiographic measures of diastolic dysfunction in rhesus macaques (Macaca mulatta).Journal of medical primatology · 2023Article
- Subclinical HMOD in Hypertension: Left Ventricular Diastolic Dysfunction.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2022Review
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Left ventricular diastolic dysfunction (LVDD) is common in hypertension and is a predictor of increased cardiovascular risk, however the effect of LVDD, detected by new guideline, on major adverse cardiac events (MACE) is unknown in hypertensive patients without known cardiovascular disease. The present study aims to evaluate LVDD in a community hypertension cohort study and assess the effect of LVDD on MACE. we studied 283 asymptomatic nonischemic patients with hypertension who had baseline echocardiogram between 2012 and 2014. Patients were followed for MACE (myocardial infarction, coronary revascularization procedures, heart failure, stroke, all-cause mortality) with mean follow-up of 5.4 years. A Cox proportional hazards model was used to assess the association of LVDD with MACE. At baseline, 35 of the 283 hypertensions were diagnosed with LVDD (12.3%) and 25 patients were women (15.5%). Women had higher frequency of LVDD than men (8%). During follow-up, there were 26.6% patients occurring MACE in the LVDD group at baseline, 9.9% patients occurring MACE in the group with normal diastolic function. In multivariable Cox regression analyses, LVDD was a stronger predictor of MACE (HR: 2.5; 95% CI: 1.20 to 5.25; c- statistics 0.805) than E/e' ratio (HR: 1.13; 95% CI: 1.04 to 1.22). LVDD was strongly associated with MACE in hypertension patients.
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