Evidence map›Paper›PMID 35697954›Full record

ArticleEJNMMI radiopharmacy and chemistry2022

Synthesis of a 2-nitroimidazole derivative N-(4-[

Arian Pérez Nario, Jenilee Woodfield, Sofia Nascimento Dos Santos, Cody Bergman, Melinda Wuest, Yasniel Babí Araújo, André Luis Lapolli, Frederick G West, Frank Wuest, Emerson Soares Bernardes

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI radiopharmacy and chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Arian Pérez Nario *Nuclear and Energy Research Institute (IPEN/CNEN - SP), São Paulo, SP, CEP 05508-000, Brazil.
Jenilee Woodfield *Department of Oncology, University of Alberta, Edmonton, AB, T6G 2R7, Canada.
Sofia Nascimento Dos SantosNuclear and Energy Research Institute (IPEN/CNEN - SP), São Paulo, SP, CEP 05508-000, Brazil.
Cody BergmanDepartment of Oncology, University of Alberta, Edmonton, AB, T6G 2R7, Canada.
Melinda WuestDepartment of Oncology, University of Alberta, Edmonton, AB, T6G 2R7, Canada.
Yasniel Babí AraújoNuclear and Energy Research Institute (IPEN/CNEN - SP), São Paulo, SP, CEP 05508-000, Brazil.
André Luis LapolliNuclear and Energy Research Institute (IPEN/CNEN - SP), São Paulo, SP, CEP 05508-000, Brazil.
Frederick G WestDepartment of Chemistry, University of Alberta, Edmonton, AB, T6G 2G2, Canada.
Frank WuestDepartment of Oncology, University of Alberta, Edmonton, AB, T6G 2R7, Canada.
Emerson Soares BernardesNuclear and Energy Research Institute (IPEN/CNEN - SP), São Paulo, SP, CEP 05508-000, Brazil. ebernardes@ipen.br.
National Nuclear Energy Commission · BRUniversity of Alberta · CA

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 142180/2015-7Fundação de Amparo à Pesquisa do Estado de São Paulo 2012/06875-6Government of Canada ELAP 2017-2018
6 · The paper itself

Abstract

backgroundTissue hypoxia is a pathological condition characterized by reducing oxygen supply. Hypoxia is a hallmark of tumor environment and is commonly observed in many solid tumors. Non-invasive imaging techniques like positron emission tomography (PET) are at the forefront of detecting and monitoring tissue hypoxia changes in vivo.

resultsWe have developed a novel

conclusionsHence, [

Indexed as

HypoxiaN-(4-[18F]fluorobenzyl)-2-(2-nitro-1H-imidazol-1-yl)acetamide ([18F]FBNA)Positron emission tomography (PET)

Identifiers

PMID35697954
PMCPMC9192864
OpenAlexW4282585028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.