Evidence map›Paper›PMID 35697942›Full record

Trial reportJournal of neural transmission (Vienna, Austria : 1996)2022

Treadmill training and physiotherapy similarly improve dual task gait performance: a randomized-controlled trial in Parkinson's disease.

Heiko Gaßner, Elmar Trutt, Sarah Seifferth, Jana Friedrich, Diana Zucker, Ziad Salhani, Werner Adler, Jürgen Winkler, Wolfgang H Jost

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of neural transmission (Vienna, Austria : 1996), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05903755 (To Understand the Effect of Speed Dependent Treadmill Training on Dual Task Performance in Patient With Parkinson's Disease.), which is not on this map. Cited by 22 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05903755 naunknown statusnot on this mapstarted 2023, after this paper: background citation

To Understand the Effect of Speed Dependent Treadmill Training on Dual Task Performance in Patient With Parkinson's Disease.

TypeinterventionalSponsorRiphah International UniversityRan2023 to 2023Enrolled22ConditionsParkinson DiseaseArmsspeed dependent treadmill training on moderate speed, speed dependent treadmill training on slow speed
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Combining transcranial electrical stimulation with training in older adults: Effects on dual-task ability.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
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  11. Neurobiology of exercise in Parkinson's disease.Journal of Parkinson's disease · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Heiko GaßnerDepartment of Molecular Neurology, Universitätsklinikum Erlangen, Molekulare Neurologie, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Schwabachanlage 6, 91054, Erlangen, Germany. heiko.gassner@uk-erlangen.de.ORCID 0000-0003-2037-9460
Elmar TruttParkinson-Klinik Ortenau, Wolfach, Germany.
Sarah SeifferthDepartment of Molecular Neurology, Universitätsklinikum Erlangen, Molekulare Neurologie, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Schwabachanlage 6, 91054, Erlangen, Germany.
Jana FriedrichDepartment of Molecular Neurology, Universitätsklinikum Erlangen, Molekulare Neurologie, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Schwabachanlage 6, 91054, Erlangen, Germany.
Diana ZuckerParkinson-Klinik Ortenau, Wolfach, Germany.
Ziad SalhaniParkinson-Klinik Ortenau, Wolfach, Germany.
Werner AdlerInstitut für Medizininformatik, Biometrie und Epidemiologie, FAU Erlangen-Nürnberg, Erlangen, Germany.
Jürgen WinklerDepartment of Molecular Neurology, Universitätsklinikum Erlangen, Molekulare Neurologie, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Schwabachanlage 6, 91054, Erlangen, Germany.
Wolfgang H JostParkinson-Klinik Ortenau, Wolfach, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Motor-cognitive dual tasks are used to investigate the interplay between gait and cognition. Dual task walking in patients with Parkinson's disease (PD) results in decreased gait speed and more importantly in an increased fall risk. There is evidence that physical training may improve gait during dual task challenge. Physiotherapy and treadmill walking are known to improve single task gait. The aim of this study was to investigate the impact of individualized physiotherapy or treadmill training on gait during dual task performance. 105 PD patients were randomly assigned to an intervention group (physiotherapy or treadmill). Both groups received 10 individual interventional sessions of 25 min each and additional group therapy sessions for 14 days. Primary outcome measure was the dual task gait speed. Secondary outcomes were additional gait parameters during dual task walking, UPDRS-III, BBS and walking capacity. All gait parameters were recorded using sensor-based gait analysis. Gait speed improved significantly by 4.2% (treadmill) and 8.3% (physiotherapy). Almost all secondary gait parameters, UPDRS-III, BBS, and walking capacity improved significantly and similarly in both groups. However, interaction effects were not observed. Both interventions significantly improved gait in patients with mild to moderate PD. However, treadmill walking did not show significant benefits compared to individualized physiotherapy. Our data suggest that both interventions improve dual task walking and therefore support safe and independent walking. This result may lead to more tailored therapeutic preferences.

Indexed as

Parkinson DiseaseExercise TestExercise TherapyGaitHumansPhysical Therapy ModalitiesWalkingDual taskGait analysisParkinson’s diseasePhysiotherapyTreadmill trainingWearable sensors

Identifiers

PMID35697942
PMCPMC9463305

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.