Evidence map›Paper›PMID 35697919›Full record

ArticleScientific reports2022

A cross-sectional multicenter linkage study of hospital admissions and mortality due to methanol poisoning in Iranian adults during the COVID-19 pandemic.

Seyed Amirhosein Mahdavi, Nasim Zamani, Rebecca McDonald, Maryam Akhgari, Ali-Asghar Kolahi, Farzad Gheshlaghi, Ali Ostadi, Ahmad Dehghan, Mohammad Moshiri, Morteza Rahbar-Taramsari and 20 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Toxidromes.Nature reviews. Disease primers · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 16 institutions in 2 countries.

Seyed Amirhosein MahdaviLegal Medicine Research Center, Legal Medicine Organization, Tehran, Iran.
Nasim Zamani *Social Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Rebecca McDonald *SERAF, Norwegian Centre for Addiction Research, University of Oslo, Oslo, Norway.
Maryam AkhgariLegal Medicine Research Center, Legal Medicine Organization, Tehran, Iran.
Ali-Asghar KolahiSocial Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Farzad GheshlaghiDepartment of Clinical Toxicology, Isfahan Clinical Toxicology Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Ali OstadiDepartment of Internal Medicine, Sina Medical Research & Training Hospital, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Ahmad DehghanAccident Prevention and Crisis Research Center, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
Mohammad MoshiriMedical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Morteza Rahbar-TaramsariDepartment of Forensic Medicine, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Mohammad DelirradDepartment of Forensic Medicine, School of Medicine, Food and Beverages Safety Research Center, Imam Khomeini Hospital, Urmia University of Medical Sciences, Urmia, Iran.
Neda MohtashamDepartment of Pediatric Clinical Toxicology, Abuzar's Children Medical Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Saeed AfzaliDepartment of Forensic Medicine, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Sara EbrahimiSchool of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Pardis ZiaeefarSchool of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Navid KhosraviDepartment of Emergency Medicine, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Amir Mohammad KazemifarDepartment of Internal Medicine, Qazvin University of Medical Sciences, Qazvin, Iran.
Mohammadreza GhadirzadehLegal Medicine Research Center, Legal Medicine Organization, Tehran, Iran.
Hoorvash FarajidanaDepartment of Emergency Medicine, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Tahereh BarghemadiDepartment of Clinical Toxicology, Loghman-Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Farangis SadeghiClinical Development Research Unit, Seyad Shirazi Hospital, Golestan University of Medial Sciences, Gorgan, Iran.
Seyed Kaveh HadeiySchool of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mehdi HadipourzadehDepartment of Clinical Toxicology, Loghman-Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Javad MesbahiQom University of Medial Sciences, Qom, Iran.
Mohammad-Reza MalekpourSocial Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mohsen ArabiDepartment of Family Medicine, Sari Medical School, Mazandaran University of Medical Sciences, Sari, Iran.
Farkhondeh JamshidiDepartment of Forensic Medicine and Social Determinant of Health Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Bita DadpourMedical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Knut Erik HovdaThe Norwegian CBRNE Centre of Medicine, Department of Acute Medicine, Oslo University Hospital, Oslo, Norway.
Hossein Hassanian-MoghaddamSocial Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. hassanian@sbmu.ac.ir.
Shahid Beheshti University of Medical Sciences · IRIranian Legal Medicine Organization · IRAhvaz Jundishapur University of Medical Sciences · IRMashhad University of Medical Sciences · IRMazandaran University of Medical Sciences · IRGolestan University · IRGuilan University of Medical Sciences · IRHamedan University of Medical Sciences · IRImam Khomeini Hospital · IRIsfahan University of Medical Sciences · IRJahrom University of Medical Sciences · IROslo University Hospital · NOQazvin University of Medical Sciences · IRShahid Sadoughi University of Medical Sciences and Health Services · IRTabriz University of Medical Sciences · IRUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A methanol poisoning outbreak occurred in Iran during the initial months of coronavirus disease 2019 (COVID-19) pandemic. We aimed to evaluate the epidemiology of the outbreak in terms of hospitalizations and deaths. A cross-sectional linkage study was conducted based on the hospitalization data collected from thirteen referral toxicology centers throughout Iran as well as mortality data obtained from the Iranian Legal Medicine Organization (LMO). Patient data were extracted for all cases aged > 19 years with toxic alcohol poisoning during the study period from February until June 2020. A total of 795 patients were hospitalized due to methanol poisoning, of whom 84 died. Median [interquartile ratio; IQR] age was 32 [26, 40] years (range 19-91 years). Patients had generally ingested alcohol for recreational motives (653, 82.1%) while 3.1% (n = 25) had consumed alcohol-based hand sanitizers to prevent or cure COVID-19 infection. Age was significantly lower in survivors than in non-survivors (P < 0.001) and in patients without sequelae vs. with sequelae (P = 0.026). Twenty non-survivors presented with a Glasgow Coma Scale (GCS) score > 8, six of whom were completely alert on presentation to the emergency departments. The time from alcohol ingestion to hospital admission was not significantly different between provinces. In East Azerbaijan province, where hemodialysis was started within on average 60 min of admission, the rate of sequelae was 11.4% (compared to 19.6% average of other provinces)-equivalent to a reduction of the odds of sequelae by 2.1 times [95% CI 1.2, 3.7; p = 0.009]. Older patients were more prone to fatal outcome and sequelae, including visual disturbances. Early arrival at the hospital can facilitate timely diagnosis and treatment and may reduce long-term morbidity from methanol poisoning. Our data thus suggest the importance of raising public awareness of the risks and early symptoms of methanol intoxication.

Indexed as

AlcoholismCOVID-19PoisoningAdultCross-Sectional StudiesHospitalizationHospitalsHumansIranMethanolPandemicsMethanol

Identifiers

PMID35697919
PMCPMC9189800
OpenAlexW4282823781

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.