Evidence map›Paper›PMID 35697818›Full record

ArticleLangenbeck's archives of surgery2022

Enhanced recovery after surgery (ERAS) program in octogenarian patients: a propensity score matching analysis on the "Lazio Network" database.

Michele Grieco, Giampaolo Galiffa, Laura Lorenzon, Giuseppe Marincola, Roberto Persiani, Roberto Santoro, Graziano Pernazza, Antonio Brescia, Emanuele Santoro, Francesco Stipa and 7 more

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Article in Langenbeck's archives of surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Michele GriecoS. Eugenio Hospital, Rome, Italy. dr.griecomichele@gmail.com.ORCID http://orcid.org/0000-0002-1978-9772
Giampaolo GaliffaS. Eugenio Hospital, Rome, Italy.
Laura LorenzonFondazione Policlinico Universitario "A. Gemelli" - IRCCS, Rome, Italy.
Giuseppe MarincolaFondazione Policlinico Universitario "A. Gemelli" - IRCCS, Rome, Italy.
Roberto PersianiFondazione Policlinico Universitario "A. Gemelli" - IRCCS, Rome, Italy.
Roberto SantoroSanta Scolastica Hospital, Cassino, Frosinone, Italy.
Graziano PernazzaSan Giovanni-Addolorata Hospital, Rome, Italy.
Antonio BresciaSant'Andrea University Hospital. "La Sapienza" University, Rome, Italy.
Emanuele SantoroSan Paolo Hospital, Civitavecchia, Rome, Italy.
Francesco StipaSan Camillo De Lellis Hospital, Rieti, Italy.
Antonio CrucittiCristo Re Hospital, Rome, Italy.
Stefano ManciniSan Filippo Neri Hospital, Rome, Italy.
Raffaele Macarone PalmieriBelcolle Hospital, Viterbo, Italy.
Massimiliano Di PaolaSan Pietro Fatebenefratelli Hospital, Rome, Italy.
Marco SacchiSanta Maria Goretti Hospital, Latina, Italy.
Massimo CarliniS. Eugenio Hospital, Rome, Italy.
Lazio Network study group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to evaluate the safety and compliance with the enhanced recovery after surgery (ERAS) protocol in octogenarian patients undergoing colorectal surgery in 12 Italian high-volume centers.

methodsA retrospective analysis was conducted in a consecutive series of patients who underwent elective colorectal surgery between 2016 and 2018. Patients were grouped by age (≥ 80 years vs < 80 years), propensity score matching (PSM) analysis was performed, and the groups were compared regarding clinical outcomes and the mean number of ERAS items applied.

resultsOut of 1646 patients identified, 310 were octogenarians. PSM identified 2 cohorts of 125 patients for the comparison of postoperative outcomes and ERAS compliance. The 2 groups were homogeneous regarding the clinical variables and mean number of ERAS items applied (11.3 vs 11.9, p-ns); however, the application of intraoperative items was greater in nonelderly patients (p 0.004). The functional recovery was similar between the two groups, as were the rates of postoperative severe complications and 30-day mortality rate. Elderly patients had more overall complications. Furthermore, the mean hospital stay was higher in the elderly group (p 0.027). Multivariable analyses documented that postoperative stay was inversely correlated with the number of ERAS items applied (p < 0.0001), whereas age ≥ 80 years significantly correlated with the overall complication rate (p 0.0419).

conclusionThe ERAS protocol is safe in octogenarian patients, with similar levels of compliance and surgical outcomes. However, octogenarian patients have a higher rate of overall complications and a longer hospital stay than do younger patients.

Indexed as

Colorectal SurgeryEnhanced Recovery After SurgeryAgedAged, 80 and overHumansLength of StayOctogenariansPostoperative ComplicationsPropensity ScoreRetrospective StudiesColorectal surgeryElderlyERAS guidelinesOncologic surgery

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.