ArticleNature communications2022
Nickel(0)-catalyzed divergent reactions of silacyclobutanes with internal alkynes.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Base-catalyzed regioselective C(spNature communications · 2026Article
- Palladium-Catalyzed Enantioselective [4 + 2] Annulation with Allenes: Direct Access to Chiral Silatetralins.JACS Au · 2026Article
- Recent Advances in Transition-Metal-Catalyzed Selective Synthesis of π‑Conjugated Silacycles: A Mini-Review.ACS omega · 2026Review
- A DMAP-enabled strategy for C(spNature communications · 2025Article
- Photo-induced ring-maintaining hydrosilylation of unactivated alkenes with hydrosilacyclobutanes.Nature communications · 2025Article
- Multimodal Precise Control Over Multiselective Carbonylation of 1,3-Enynes.Journal of the American Chemical Society · 2025Article
- Enantioselective construction of silicon-stereogenic vinylsilanes from simple alkenes.Nature communications · 2025Article
- Carbon-silicon-switch effect in enantioselective construction of silicon-stereogenic center from silacyclohexadienones.Nature communications · 2024Article
- Organocatalytic asymmetric synthesis of Si-stereogenic silacycles.Nature communications · 2024Article
- Evolution of organic phosphor through precision regulation of nonradiative decay.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- An unusual autocatalysis with an air-stable Pd complex to promote enantioselective synthesis of Si-stereogenic enynes.Chemical science · 2023Article
- Stereospecific nickel-catalyzed [4+2] heteroannulation of alkynes with aminophosphanes.Science advances · 2023Article
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4 authors.
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Abstract
Transition metal-catalyzed reactions of silacyclobutanes with a variety of π units have attracted much attention and become one of the most straightforward and efficient approaches to rapidly access structurally diverse organosilicon compounds. However, the reaction of silacyclobutanes with alkynes still suffers from some limitations: (1) internal alkynes remain challenging substrates; (2) expensive Pd- or Rh-based catalysts have been employed in all existing systems; (3) controlling chemodivergence has not yet been realized. Herein we realize Ni-catalyzed chemodivergent reactions of silacyclobutanes with alkynes. In comparison with the previous Pd or Rh catalytic systems, our Ni-catalytic system features: 1) complementary substrate scope; 2) ligand-controlled chemodivergence; 3) low cost. The ligand precisely dictates the pathway selectivity, leading to the divergent formation of (benzo)silacyclohexenes and allyl vinylsilanes. Moreover, we demonstrate that employment of a chiral phosphine ligand is capable of forming silicon-stereogenic allyl vinylsilanes in high yields and enantioselectivities. In addition, DFT calculation is performed to elucidate the origin of the switchable selectivities, which is mainly attributed to different ligand steric effects.
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