Evidence map›Paper›PMID 35697456›Full record

ArticleBMJ open2022

Chronic lung lesions in COVID-19 survivors: predictive clinical model.

Carlos Roberto Ribeiro Carvalho, Rodrigo Caruso Chate, Marcio Valente Yamada Sawamura, Michelle Louvaes Garcia, Celina Almeida Lamas, Diego Armando Cardona Cardenas, Daniel Mario Lima, Paula Gobi Scudeller, João Marcos Salge, Cesar Higa Nomura and 3 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Carlos Roberto Ribeiro CarvalhoInstituto do Coração-Divisão de Pneumologia, Universidade de São Paulo Hospital das Clínicas, Sao Paulo, Brazil carlos.carvalho@hc.fm.usp.br.ORCID 0000-0002-1618-8509
Rodrigo Caruso ChateInstituto de Radiologia, Universidade de São Paulo Hospital das Clínicas, Sao Paulo, Brazil.
Marcio Valente Yamada SawamuraInstituto de Radiologia, Universidade de São Paulo Hospital das Clínicas, Sao Paulo, Brazil.
Michelle Louvaes GarciaInstituto do Coração-Divisão de Pneumologia, Universidade de São Paulo Hospital das Clínicas, Sao Paulo, Brazil.
Celina Almeida LamasInstituto do Coração-Divisão de Pneumologia, Universidade de São Paulo Hospital das Clínicas, Sao Paulo, Brazil.
Diego Armando Cardona CardenasInstituto do Coração-Divisão de Informática, Universidade de São Paulo Hospital das Clínicas, Sao Paulo, Brazil.
Daniel Mario LimaInstituto do Coração-Divisão de Informática, Universidade de São Paulo Hospital das Clínicas, Sao Paulo, Brazil.ORCID 0000-0002-7818-6103
Paula Gobi ScudellerInstituto do Coração-Divisão de Pneumologia, Universidade de São Paulo Hospital das Clínicas, Sao Paulo, Brazil.
João Marcos SalgeInstituto do Coração-Divisão de Pneumologia, Universidade de São Paulo Hospital das Clínicas, Sao Paulo, Brazil.
Cesar Higa NomuraInstituto de Radiologia, Universidade de São Paulo Hospital das Clínicas, Sao Paulo, Brazil.
Marco Antonio GutierrezInstituto do Coração-Divisão de Pneumologia, Universidade de São Paulo Hospital das Clínicas, Sao Paulo, Brazil.
Members of the HCFMUSP COVID-19 Study Group
Members of the HCFMUSP Covid-19 Study Group
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to propose a simple, accessible and low-cost predictive clinical model to detect lung lesions due to COVID-19 infection.

designThis prospective cohort study included COVID-19 survivors hospitalised between 30 March 2020 and 31 August 2020 followed-up 6 months after hospital discharge. The pulmonary function was assessed using the modified Medical Research Council (mMRC) dyspnoea scale, oximetry (SpO

settingA tertiary hospital in Sao Paulo, Brazil.

participants749 eligible RT-PCR-confirmed SARS-CoV-2-infected patients aged ≥18 years. PRIMARY OUTCOME MEASURE: A predictive clinical model for lung lesion detection on chest CT.

resultsThere were 470 patients (63%) that had at least one sign of pulmonary involvement and were eligible for CT. Almost half of them (48%) had significant pulmonary abnormalities, including ground-glass opacities, parenchymal bands, reticulation, traction bronchiectasis and architectural distortion. The machine learning model, including the results of 257 patients with complete data on mMRC, SpO

conclusionA predictive clinical model based on CXR, mMRC, oximetry and spirometry data can accurately screen patients with lung lesions after SARS-CoV-2 infection. Given that these examinations are highly accessible and low cost, this protocol can be automated and implemented in different countries for early detection of COVID-19 sequelae.

Indexed as

COVID-19AdolescentAdultBrazilHumansLungProspective StudiesSARS-CoV-2Survivorschest imagingCOVID-19respiratory medicine (see thoracic medicine)

Identifiers

PMID35697456
PMCPMC9195157
OpenAlexW4282555757

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.