Evidence map›Paper›PMID 35696573›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Temporal relations between peripheral and central arousals in good and poor sleepers.

Ana Ribeiro, Rachel Gabriel, Bernardo Garcia, Casey Cuccio, William Aqeel, Alejandro Moreno, Colby Landeen, Arlene Hurley, Neil Kavey, Donald Pfaff

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Effects of motivational music on sleep quality for caregivers of patients with advanced cancer: a randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Trial
  2. From classic to cutting-edge: technological approaches to respiratory physiological signals in assessing sleep-disordered breathing.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Ana RibeiroLaboratory of Neurobiology and Behavior, The Rockefeller University, New York, NY 10065.
Rachel GabrielDivision of Natural Sciences, College of Mount Saint Vincent, New York, NY 10471.
Bernardo GarciaDivision of Natural Sciences, College of Mount Saint Vincent, New York, NY 10471.
Casey CuccioDivision of Natural Sciences, College of Mount Saint Vincent, New York, NY 10471.
William AqeelDivision of Natural Sciences, College of Mount Saint Vincent, New York, NY 10471.
Alejandro MorenoDivision of Natural Sciences, College of Mount Saint Vincent, New York, NY 10471.
Colby LandeenDivision of Natural Sciences, College of Mount Saint Vincent, New York, NY 10471.
Arlene HurleyLaboratory of Neurobiology and Behavior, The Rockefeller University, New York, NY 10065.ORCID 0000-0003-0575-0233
Neil KaveyLaboratory of Neurobiology and Behavior, The Rockefeller University, New York, NY 10065.ORCID 0000-0002-4199-2777
Donald PfaffLaboratory of Neurobiology and Behavior, The Rockefeller University, New York, NY 10065.
College of Mount Saint Vincent · USRockefeller University · USColumbia University · US

Funding

Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational SuccessUL1TR001866 · NCATS · ROCKEFELLER UNIVERSITY · PI COLLER, BARRY, KRUEGER, JAMES G · 2016 to 2025
$40.6M
NCATS NIH HHS UL1 TR001866
6 · The paper itself

Abstract

Good sleepers and patients with insomnia symptoms (poor sleepers) were tracked with two measures of arousal; conventional polysomnography (PSG) for electroencephalogram (EEG) assessed cortical arousals, and a peripheral arterial tonometry device was used for the detection of peripheral nervous system (PNS) arousals associated with vasoconstrictions. The relationship between central (cortical) and peripheral (autonomic) arousals was examined by evaluating their close temporal dynamics. Cortical arousals almost invariably were preceded and followed by peripheral activations, while large peripheral autonomic arousals were followed by cortical arousals only half of the time. The temporal contiguity of these two types of arousals was altered in poor sleepers, and poor sleepers displayed a higher number of cortical and peripheral arousals compared with good sleepers. Given the difference in the number of peripheral autonomic arousals between good and poor sleepers, an evaluation of such arousals could become a means of physiologically distinguishing poor sleepers.

Indexed as

ArousalAutonomic Nervous SystemCerebral CortexSleep Initiation and Maintenance DisordersElectroencephalographyHumansPolysomnographyarousalautonomiccorticalinsomniasympathetic

Identifiers

PMID35696573
PMCPMC9231500
OpenAlexW4282559127

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.