Evidence map›Paper›PMID 35696571›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

Boris Simonetti, James L Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A Lewis, Kate J Heesom and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Covid-19 and risk of acute pancreatitis: What beyond.Journal of cellular and molecular medicine · 2024
    Article
  5. Article
  6. Article
  7. Architecture of the ESCPE-1 membrane coat.Nature structural & molecular biology · 2023
    Article
  8. Review
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  10. Article
  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 3 countries.

Boris SimonettiSchool of Biochemistry, Faculty of Life Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom.
James L DalySchool of Biochemistry, Faculty of Life Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom.ORCID 0000-0002-4551-1256
Lorena Simón-GraciaLaboratory of Precision and Nanomedicine, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu 50411, Estonia.ORCID 0000-0003-1825-8723
Katja KleinSchool of Cellular and Molecular Medicine, Faculty of Life Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom.
Saroja WeeratungaInstitute for Molecular Bioscience, The University of Queensland, St. Lucia, QLD 4072, Australia.
Carlos Antón-PlágaroSchool of Biochemistry, Faculty of Life Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom.ORCID 0000-0002-7497-0080
Allan TobiLaboratory of Precision and Nanomedicine, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu 50411, Estonia.
Lorna HodgsonSchool of Biochemistry, Faculty of Life Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom.ORCID 0000-0001-6373-4405
Philip A LewisProteomics Facility, School of Biochemistry, Faculty of Life Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom.ORCID 0000-0002-2868-2459
Kate J HeesomProteomics Facility, School of Biochemistry, Faculty of Life Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom.ORCID 0000-0002-5418-5392
Deborah K ShoemarkSchool of Biochemistry and BrisSynBio Centre, Faculty of Life Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom.ORCID 0000-0002-1240-8463
Andrew D DavidsonSchool of Cellular and Molecular Medicine, Faculty of Life Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom.ORCID 0000-0002-1136-4008
Brett M CollinsInstitute for Molecular Bioscience, The University of Queensland, St. Lucia, QLD 4072, Australia.ORCID 0000-0002-6070-3774
Tambet TeesaluLaboratory of Precision and Nanomedicine, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu 50411, Estonia.
Yohei YamauchiSchool of Cellular and Molecular Medicine, Faculty of Life Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom.ORCID 0000-0002-8233-9133
Peter J CullenSchool of Biochemistry, Faculty of Life Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom.
University of Bristol · GBUniversity of Tartu · EEThe University of Queensland · AU

Funding

Department of Health | National Health and Medical Research Council (NHMRC) APP1136021UKRI | Biotechnology and Biological Sciences Research Council (BBSRC) BB/L01386X/1UKRI | Medical Research Council (MRC) MR/L007363/1UKRI | Medical Research Council (MRC) MR/P018807/1UKRI | Medical Research Council (MRC) MR/W005611/1Wellcome TrustWellcome Trust (WT) 104568/Z/14/ZWellcome Trust (WT) 20260/Z/20/ZWellcome Trust (WT) 203959/Z/16/Z
6 · The paper itself

Abstract

Endosomal sorting maintains cellular homeostasis by recycling transmembrane proteins and associated proteins and lipids (termed "cargoes") from the endosomal network to multiple subcellular destinations, including retrograde traffic to the

Indexed as

COVID-19EndosomesHost-Pathogen InteractionsNeuropilin-1SARS-CoV-2CRISPR-Cas SystemsGene DeletionHumansNanoparticlesProteomicsSorting NexinsSpike Glycoprotein, CoronavirusNeuropilin-1NRP1 protein, humanSorting NexinsSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2COVID-19endosomeNeuropilin-1SARS-CoV-2sorting nexin

Identifiers

PMID35696571
PMCPMC9231623
OpenAlexW4282590979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.