ArticleProceedings of the National Academy of Sciences of the United States of America2022
Functional evidence supports adaptive plant chemical defense along a geographical cline.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 45 citations in OpenAlex.
- Structural innovation in the evolution of plant chemical defense.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Article
- Divergent dietary and defensive adaptations of closely related coexisting seed bugs.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Entomopathogenic Nematode Species Vary in Their Behavior and Virulence in Response to Cardiac Glycosides Within and Around Insect Hosts.Journal of chemical ecology · 2025Article
- Plant chemical diversity enhances defense against herbivory.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Substrate Specificity of ABCB Transporters Predicted by Docking Simulations Can Be Confirmed by Experimental Tests.Molecules (Basel, Switzerland) · 2024Article
- Potent Nitrogen-containing Milkweed Toxins are Differentially Regulated by Soil Nitrogen and Herbivore-induced Defense.Journal of chemical ecology · 2024Article
- Cardenolides in the defensive fluid of adult large milkweed bugs have differential potency on vertebrate and invertebrate predator NaRoyal Society open science · 2024Article
- A nutrition-defence trade-off drives diet choice in a toxic plant generalist.Proceedings. Biological sciences · 2023Article
- Compound-Specific Behavioral and Enzymatic Resistance to Toxic Milkweed Cardenolides in a Generalist Bumblebee Pollinator.Journal of chemical ecology · 2023Article
- No-cost meals might not exist for insects feeding on toxic plants.Biology open · 2023Review
- Tissue-specific plant toxins and adaptation in a specialist root herbivore.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Antioxidant availability trades off with warning signals and toxin sequestration in the large milkweed bug (Ecology and evolution · 2023Article
- New Structures, Spectrometric Quantification, and Inhibitory Properties of Cardenolides fromMolecules (Basel, Switzerland) · 2022Article
- Profile of Anurag A. Agrawal.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Environmental clines in organismal defensive traits are usually attributed to stronger selection by enemies at lower latitudes or near the host's range center. Nonetheless, little functional evidence has supported this hypothesis, especially for coevolving plants and herbivores. We quantified cardenolide toxins in seeds of 24 populations of common milkweed (
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.