ArticleAmerican journal of respiratory and critical care medicine2022
Endogenous Retroviral Elements Generate Pathologic Neutrophils in Pulmonary Arterial Hypertension.
Open access · hybridAbstract read
In one paragraph
Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 41 citations in OpenAlex.
- SPECTRA-based Detection of Drug-Induced Hepatotoxicity through Extracellular Vesicle Analysis.Sensors and actuators. B, Chemical · 2026Article
- Targeting neutrophil extracellular traps (NETs): a promising immunotherapeutic approach for pulmonary diseases.Molecular biology reports · 2026Review
- Advances in the pathogenesis and clinical management of pulmonary hypertension.Medical review (2021) · 2026Review
- The emerging role of integrin signaling in pulmonary vascular disease.American journal of physiology. Lung cellular and molecular physiology · 2026Review
- Interconnected Pathways and Therapeutic Implications for Cardiovascular Aging and Diseases.JACC. Asia · 2026Review
- Systemic immune-inflammation Index and blood pressure control are independent and interactive predictors of atrial fibrillation recurrence after ablation.Frontiers in cardiovascular medicine · 2026Article
- Chronic Reactivation of Persistent Human Herpesviruses EBV, HHV-6 and VZV and Heightened Anti-dUTPase IgG Antibodies Are a Recurrent Hallmark in Post-Infectious ME/CFS and is Associated With Fatigue.Journal of medical virology · 2026Article
- The Role of Toll-like Receptors and Viral Infections in the Pathogenesis and Progression of Pulmonary Arterial Hypertension-A Narrative Review.International journal of molecular sciences · 2025Review
- Plasma Preparation Strategies for Extracellular Vesicle-Based Biomarkers in Metastatic Castration-Resistant Prostate Cancer.Journal of extracellular biology · 2025Article
- Extracellular matrix in vascular homeostasis and disease.Nature reviews. Cardiology · 2025Review
- Altered maturation and activation state of circulating monocytes is associated with their enhanced recruitment in pulmonary arterial hypertension.Respiratory research · 2025Article
- SHINE: SERS-based Hepatotoxicity detection using Inference from Nanoscale Extracellular vesicle content.bioRxiv : the preprint server for biology · 2025Article
- Microbiome-Immune Interaction in Pulmonary Arterial Hypertension: What Have We Missed?Research (Washington, D.C.) · 2025Review
- Research progress on the cross-regulation between ferroptosis and immunogenic cell death in tumor micro-environment.Frontiers in oncology · 2025Review
- Natural products targeting the immune-metabolic regulatory network in pulmonary hypertension: mechanisms, classification, and therapeutic prospects.Frontiers in pharmacology · 2025Review
- Mechanisms of lung endothelial cell injury and survival in pulmonary arterial hypertension.American journal of physiology. Lung cellular and molecular physiology · 2024Review
- Advancing osteoarthritis therapy with GMOCS hydrogel-loaded BMSCs-exos.Journal of nanobiotechnology · 2024Article
- Immunotherapy for Pulmonary Arterial Hypertension: From the Pathogenesis to Clinical Management.International journal of molecular sciences · 2024Review
- Retrotransposons in Werner syndrome-derived macrophages trigger type I interferon-dependent inflammation in an atherosclerosis model.Nature communications · 2024Article
- Endogenous Retroviruses Unveiled: A Comprehensive Review of Inflammatory Signaling/Senescence-Related Pathways and Therapeutic Strategies.Aging and disease · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
30 authors at 8 institutions in 4 countries.
Shalina TaylorVera Moulton Wall Center for Pulmonary Vascular Diseases.
Sarasa IsobeVera Moulton Wall Center for Pulmonary Vascular Diseases.
Aiqin CaoVera Moulton Wall Center for Pulmonary Vascular Diseases.
Kévin ContrepoisStanford Cardiovascular Institute.
Bérénice A BenayounLeonard Davis School of Gerontology and.
Lihua JiangStanford Cardiovascular Institute.
Lingli WangVera Moulton Wall Center for Pulmonary Vascular Diseases.
Stavros MelemenidisDepartment of Radiation Oncology.
Mehmet O OzenDepartment of Radiology Canary Center for Cancer Early Detection.
Shoichiro OtsukiVera Moulton Wall Center for Pulmonary Vascular Diseases.
Tsutomu ShinoharaVera Moulton Wall Center for Pulmonary Vascular Diseases.
Andrew J SweattVera Moulton Wall Center for Pulmonary Vascular Diseases.
Jordan KaplanVera Moulton Wall Center for Pulmonary Vascular Diseases.
Jan-Renier MoonenVera Moulton Wall Center for Pulmonary Vascular Diseases.
David P MarcianoStanford Cardiovascular Institute.
Mingxia GuVera Moulton Wall Center for Pulmonary Vascular Diseases.
Kazuya MiyagawaVera Moulton Wall Center for Pulmonary Vascular Diseases.
Brandon HayesLinac Coherent Light Source, SLAC National Accelerator Laboratory, Menlo Park, California.
Raymond G SierraLinac Coherent Light Source, SLAC National Accelerator Laboratory, Menlo Park, California.
Christopher J KupitzLinac Coherent Light Source, SLAC National Accelerator Laboratory, Menlo Park, California.
Patricia A Del RosarioVera Moulton Wall Center for Pulmonary Vascular Diseases.
Andrew HsiVera Moulton Wall Center for Pulmonary Vascular Diseases.
A A Roger ThompsonVera Moulton Wall Center for Pulmonary Vascular Diseases.ORCID 0000-0002-0717-4551
Maria E ArizaDepartment of Cancer Biology and Genetics and.
Utkan DemirciDepartment of Radiation Oncology.
Roham T ZamanianVera Moulton Wall Center for Pulmonary Vascular Diseases.
Francois HaddadStanford Cardiovascular Institute.
Mark R NicollsVera Moulton Wall Center for Pulmonary Vascular Diseases.
Michael P SnyderStanford Cardiovascular Institute.
Marlene RabinovitchVera Moulton Wall Center for Pulmonary Vascular Diseases.ORCID 0000-0001-7886-7104
Cardiovascular Institute of the South · USPulmonary and Critical Care Associates · USSLAC National Accelerator Laboratory · USStanford University · USCanary Institute of Cancer Research · ESCincinnati Children's Hospital Medical Center · USThe Ohio State University Wexner Medical Center · USUniversity of Southern California · US
Funding
MICHIGAN INSTITUTE FOR CLINICAL AND HEALTH RESEARCH (MICHR) (UL1): (BPCA)UL1RR024986 · NCRR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SHANLEY, THOMAS P. · 2007 to 2011
$51.2MThe Cellular Response to Elafin in PAHP01HL108797 · NHLBI · STANFORD UNIVERSITY · PI RABINOVITCH, MARLENE · 2011 to 2021
$19.7MStanford Islet Research CoreP30DK116074 · NIDDK · STANFORD UNIVERSITY · PI Seung K Kim · 2017 to 2026
$19.5MPulmonary Hypertension in Genetically Modified MiceR01HL074186 · NHLBI · STANFORD UNIVERSITY · PI RABINOVITCH, MARLENE · 2004 to 2022
$10.4MPulmonary Hypertension Breakthrough InitiativeR24HL123767 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ALDRED, MICHEALA A, ERZURUM, SERPIL C. · 2014 to 2017
$10.1MThe BMP-PPARy Axis and Pulmonary HypertensionR01HL087118 · NHLBI · STANFORD UNIVERSITY · PI RABINOVITCH, MARLENE · 2008 to 2022
$7.2MEndothelial Injury, BMPR2 Dysfunction and Macrophage Activation Cause EndMT and PAHR01HL138473 · NHLBI · STANFORD UNIVERSITY · PI Mark Robert Nicolls, Marlene Rabinovitch · 2017 to 2026
$4.9MIntegrative Omics as a Discovery Tool for Pulmonary HypertensionR01HL122887 · NHLBI · STANFORD UNIVERSITY · PI NICOLLS, MARK ROBERT, RABINOVITCH, MARLENE · 2015 to 2018
$4.1MStanford Training Program in Lung BiologyT32HL129970 · NHLBI · STANFORD UNIVERSITY · PI CORNFIELD, DAVID N., NICOLLS, MARK ROBERT · 2016 to 2025
$3.2MHigh Shear Stress Alters Gene Regulation in Pulmonary Arterial HypertensionR01HL152134 · NHLBI · STANFORD UNIVERSITY · PI RABINOVITCH, MARLENE · 2021 to 2024
$2.9MRegulatory T Cells and Pulmonary HypertensionR01HL158714 · NHLBI · PALO ALTO VETERANS INSTIT FOR RESEARCH · PI NICOLLS, MARK ROBERT · 2021 to 2024
$2.5MReclassifying Pulmonary Arterial Hypertension Into Immune Phenotypes Using Machine LearningK23HL151892 · NHLBI · STANFORD UNIVERSITY · PI SWEATT, ANDREW JOHN · 2020 to 2024
$942kBLRD VA I01 BX005628British Heart Foundation FS/18/13/33281NCRR NIH HHS S10 RR026780NCRR NIH HHS UL1 RR024986NHLBI NIH HHS K23 HL151892NHLBI NIH HHS K99 HL135258NHLBI NIH HHS K99 HL145097NHLBI NIH HHS K99 HL 1450970NHLBI NIH HHS K99/R00 HL135258NHLBI NIH HHS P01 HL108797NHLBI NIH HHS P01 HL108797-04W1NHLBI NIH HHS R00 HL135258NHLBI NIH HHS R00 HL145097NHLBI NIH HHS R01 HL074186NHLBI NIH HHS R01 HL087118NHLBI NIH HHS R01 HL122887NHLBI NIH HHS R01 HL138473NHLBI NIH HHS R01 HL152134NHLBI NIH HHS R01 HL158714NHLBI NIH HHS R24 HL123767NHLBI NIH HHS T32 HL129970NIA NIH HHS R00 AG049934NIDDK NIH HHS P30 DK116074NIH HHS S10 OD025212NIH HHS T32 HL129970-02
Abstract
PubMed holds no abstract for this paper.
Indexed as
Endogenous RetrovirusesHypertension, PulmonaryPulmonary Arterial HypertensionAnimalsAntiviral AgentsElafinFamilial Primary Pulmonary HypertensionHumansIntegrinsLeukocyte ElastaseMiceNeutrophilsProteomicsVinculinAntiviral AgentsElafinIntegrinsLeukocyte ElastaseVinculinantiviral agentselafinextracellular vesicles (EVs)leukocyte elastasevinculin
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.