ArticleMolecular plant pathology2022
The secreted ribonuclease T2 protein FoRnt2 contributes to Fusarium oxysporum virulence.
Article in Molecular plant pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 29 citations in OpenAlex.
- The Conserved Guanyl-Specific Ribonuclease T1 Effector EC19 Is Required for Full Virulence of the Vascular Wilt Fungus Fusarium oxysporum on Tomato.Molecular plant pathology · 2026Article
- Solanaceous vegetables andHorticulture research · 2026Article
- The fungi effector VmRnt2 fromHorticulture research · 2026Article
- Lysine crotonylation enhances fungal effector activity and promotes invasion of host plants.Plant communications · 2026Article
- Interaction Between Glycoside Hydrolase FsGH28c fromInternational journal of molecular sciences · 2025Article
- Proteomic Analysis of theJournal of fungi (Basel, Switzerland) · 2025Article
- Validation ofJournal of fungi (Basel, Switzerland) · 2025Article
- FoCup, a secreted protein, is essential for virulence ofFrontiers in microbiology · 2025Article
- Beyond salt tolerance: SOS1-13's pivotal role in regulating the immune response toFrontiers in plant science · 2025Article
- The secreted protein FonCHRD is essential for vegetative growth, asexual reproduction, and pathogenicity in watermelon Fusarium wilt fungus.Crop health · 2024Article
- The Ubiquitous Wilt-Inducing PathogenPathogens (Basel, Switzerland) · 2024Review
- Article
- A ribonuclease T2 protein FocRnt2 contributes to the virulence of Fusarium oxysporum f. sp. cubense tropical race 4.Molecular plant pathology · 2024Article
- VmPacC-mediated pH regulation of Valsa mali confers to host acidification identified by comparative proteomics analysis.Stress biology · 2023Article
- The secreted FolAsp aspartic protease facilitates the virulence ofFrontiers in microbiology · 2023Article
- The secreted ribonuclease T2 protein FoRnt2 contributes to Fusarium oxysporum virulence.Molecular plant pathology · 2022Article
- The secreted FoAPY1 peptidase promotesFrontiers in microbiology · 2022Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Secreted RNase proteins have been reported from only a few pathogens, and relatively little is known about their biological functions. Fusarium oxysporum is a soilborne fungal pathogen that causes Fusarium wilt, one of the most important diseases on tomato. During the infection of F. oxysporum, some proteins are secreted that modulate host plant immunity and promote pathogen invasion. In this study, we identify an RNase, FoRnt2, from the F. oxysporum secretome that belongs to the ribonuclease T2 family. FoRnt2 possesses an N-terminal signal peptide and can be secreted from F. oxysporum. FoRnt2 exhibited ribonuclease activity and was able to degrade the host plant total RNA in vitro dependent on the active site residues H80 and H142. Deletion of the FoRnt2 gene reduced fungal virulence but had no obvious effect on mycelial growth and conidial production. The expression of FoRnt2 in tomato significantly enhanced plant susceptibility to pathogens. These data indicate that FoRnt2 is an important contributor to the virulence of F. oxysporum, possibly through the degradation of plant RNA.
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