ArticleJournal of food and drug analysis2020
Anti-inflammatory effects of peptides from a marine algicolous fungus Acremonium sp. NTU492 in BV-2 microglial cells.
Article in Journal of food and drug analysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 27 citations in OpenAlex.
- Spiro-Linked Polyketides from Cultures ofJournal of natural products · 2026Article
- Antioxidant, Anti-Inflammatory and Anticancer Peptides from Extreme Marine Environments.Antioxidants (Basel, Switzerland) · 2026Review
- Novel inducible nitric oxide synthase-inhibiting cytochalasins from an oyster-derived fungus Westerdykella dispersa Ca4-13: structural insights and molecular docking analysis.Botanical studies · 2025Article
- Anti-neuroinflammatory polyketides from the medicinal herb-derived fungal strain Didymocyrtis brachylaenae Km1530.Journal of food and drug analysis · 2025Article
- Natural Products from Marine-Derived Fungi with Anti-Inflammatory Activity.Marine drugs · 2024Review
- Chemical constituents from a marine medicinal brown alga-derived Xylaria acuta SC1019.Journal of food and drug analysis · 2024Article
- Recent Advances in Chemistry and Bioactivities of Secondary Metabolites from the GenusJournal of fungi (Basel, Switzerland) · 2024Review
- Chemical constituents from the medicinal herb-derived fungus Chaetomium globosum Km1226.Botanical studies · 2023Article
- Chemical Constituents and Anti-Angiogenic Principles from a Marine AlgicolousMolecules (Basel, Switzerland) · 2022Article
- Exploring Peptaibol's Profile, Antifungal, and Antitumor Activity of Emericellipsin A ofMolecules (Basel, Switzerland) · 2022Article
- Bioactive compounds from an endophytic fungi Nigrospora aurantiaca.Botanical studies · 2021Article
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Authors and funding
8 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Located in tropical and subtropical region, Taiwan is an island with high algal species diversity. In this study, a number of fungal strains were isolated from marine macroalgae collected from northeastern intertidal zone of Taiwan. Preliminary anti-inflammatory screening has shown that the methanolic extracts of solid fermented products of the red alga Mastophora rosea-derived fungal strain Acremonium sp. NTU492 exhibited significant bioactivity. In an attempt to disclose the active principles from this fungal strain, a series of separation and purification was thus undertaken, which has led to the isolation and characterization of seven compounds including four new peptides, namely acrepeptins A-D (1-4), along with previously reported destruxin B (5), guangomide A (6), and guangomide B (7). Their structures were elucidated by spectroscopic analysis and compared with literatures. Of these, acrepeptins A (1) and C (3) showed markedly inhibitory activities on nitric oxide production in lipopolysaccharide-activated microglial BV-2 cells with IC
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