Evidence map›Paper›PMID 35696048›Full record

ReviewMolecular biology reports2022

Immune cell metabolism and metabolic reprogramming.

Chenchen Hu, Yuxin Xuan, Xiyang Zhang, Yang Liu, Shuya Yang, Kun Yang

Open access · bronzeAbstract readReview
In one paragraph

Review in Molecular biology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 103 citations in OpenAlex.

  1. Trial
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  11. Immune Dysregulation in Branched Chain Organic Acidemias.Journal of inherited metabolic disease · 2026
    Review
  12. Depletion of myeloid-derived Zbtb46Journal of advanced research · 2026
    Article
  13. Article
  14. Article
  15. Review
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  20. Mechanisms Underlying Altitude-Induced and Group 3 Pulmonary Hypertension.International journal of molecular sciences · 2026
    Review

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chenchen Hu *Department of Immunology, The Fourth Military Medical University, #169 Changle West Road, Xi'an, 710032, Shaanxi, People's Republic of China.
Yuxin Xuan *School of Basic Medicine, The Fourth Military Medical University, Xi'an, 710032, Shaanxi, People's Republic of China.
Xiyang ZhangDepartment of Immunology, The Fourth Military Medical University, #169 Changle West Road, Xi'an, 710032, Shaanxi, People's Republic of China.
Yang LiuDepartment of Immunology, The Fourth Military Medical University, #169 Changle West Road, Xi'an, 710032, Shaanxi, People's Republic of China.
Shuya YangDepartment of Immunology, The Fourth Military Medical University, #169 Changle West Road, Xi'an, 710032, Shaanxi, People's Republic of China. yangshuxiaoya@163.com.
Kun YangDepartment of Immunology, The Fourth Military Medical University, #169 Changle West Road, Xi'an, 710032, Shaanxi, People's Republic of China. yangkunkun@fmmu.edu.cn.ORCID http://orcid.org/0000-0003-0305-6256
Air Force Medical University · CN

Funding

National Natural Science Foundation of China No. 82073154Natural Science Foundation of Shaanxi Province No. 2020SF-200Scientific Research Fund BWS19J011
6 · The paper itself

Abstract

Energy metabolism maintains the activation of intracellular and intercellular signal transduction, and plays a crucial role in immune response. Under environmental stimulation, immune cells change from resting to activation and trigger metabolic reprogramming. The immune system cells exhibit different metabolic characteristics when performing functions. The study of immune metabolism provides new insights into the function of immune cells, including how they differentiate, migrate and exert immune responses. Studies of immune cell energy metabolism are beginning to shed light on the metabolic mechanism of disease progression and reveal new ways to target inflammatory diseases such as autoimmune diseases, chronic viral infections, and cancer. Here, we discussed the relationship between immune cells and metabolism, and proposed the possibility of targeted metabolic process for disease treatment.

Indexed as

Autoimmune DiseasesNeoplasmsEnergy MetabolismHumansImmune SystemSignal TransductionImmune cellsImmune metabolismMetabolic reprogrammingTargeted therapy

Identifiers

PMID35696048
PMCPMC9189272
OpenAlexW4282831854

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.