Evidence map›Paper›PMID 35695929›Full record

SynthesisJournal of cancer research and clinical oncology2022

Diet and gastric cancer risk: an umbrella review of systematic reviews and meta-analyses of prospective cohort studies.

Shu-Jun Liu, Pi-Di Huang, Jia-Min Xu, Qian Li, Jian-Hui Xie, Wen-Zhen Wu, Chen-Tong Wang, Xiao-Bo Yang

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Journal of cancer research and clinical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Environmental factors in gastric carcinogenesis and preventive intervention strategies.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2025
    Review
  5. Screening for and surveillance of premalignant conditions of the stomach.Best practice & research. Clinical gastroenterology · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Shu-Jun LiuSchool of Second Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China.
Pi-Di HuangSchool of Second Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China.
Jia-Min XuSchool of Second Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China.
Qian LiState Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, No. 36, Yuexiu District, Guangzhou, 510000, Guangdong, People's Republic of China.
Jian-Hui XieState Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, No. 36, Yuexiu District, Guangzhou, 510000, Guangdong, People's Republic of China.
Wen-Zhen WuState Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, No. 36, Yuexiu District, Guangzhou, 510000, Guangdong, People's Republic of China.
Chen-Tong WangThe First Clinical Medical College, Heilongjiang University of Traditional Chinese Medicine, Harbin, China.
Xiao-Bo YangState Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, No. 36, Yuexiu District, Guangzhou, 510000, Guangdong, People's Republic of China. yangxiaobo621@126.com.ORCID http://orcid.org/0000-0002-0613-489X
Guangzhou University of Chinese Medicine · CNHeilongjiang University · CN

Funding

Collaborative Innovation Center for Modern Science and Technology and Industrial Development of Jiangxi Traditional Medicine YN2018ZD02National Natural Science Foundation of China 81673845Natural Science Foundation of Shaanxi Provincial Department of Education 2019A1515010638Science and Technology Planning Project of Guangdong Province 2016A020226036Science and Technology Planning Project of Guangdong Province 2017B030314166
6 · The paper itself

Abstract

backgroundSeveral systematic reviews and meta-analyses evaluated the associations between dietary factors and the incidence of gastric cancer (GC).

objectivesTo evaluate the strength and validity of existing evidence, we conducted an umbrella review of published systematic reviews and meta-analyses that investigated the association between diets and GC incidence.

methodsWe searched the PubMed, Embase, and Cochrane databases for systematic reviews and meta-analyses of prospective cohort studies investigating the association between dietary factors and GC risk. For each association, we recalculated the adjusted summary estimates with their 95% confidence interval (CI) and 95% prediction interval (PI) using a random-effects model. We used the I

resultsFinally, we identified 16 meta-analyses that described 57 associations in this umbrella review. Of the 57 associations, eight were statistically significant using random-effects, thirteen demonstrated substantial heterogeneity between studies (I

conclusionsOur findings support the dietary recommendations for preventative GC, emphasizing lower intake of alcohol and foods preserved by salting. New evidence suggests a possible role for total fruit, citrus fruit, carotenoids, and vitamin E. More research is needed on diets with lower quality evidence. REGISTRATION NUMBER: CRD42021255115.

Indexed as

Stomach NeoplasmsCarotenoidsDietHumansProspective StudiesSystematic Reviews as TopicVitamin ECarotenoidsVitamin EDietEvidenceGastric cancerMeta-analysisUmbrella review

Identifiers

PMID35695929
PMCPMC11801035
OpenAlexW4282839050

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.