Evidence map›Paper›PMID 35695620›Full record

ArticleGut microbes

Fecal carriage of

Lars M M Vliex, Giang N Le, Marina Fassarella, Dorien Reijnders, Gijs H Goossens, Erwin G Zoetendal, John Penders, Ellen E Blaak

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Lars M M VliexDepartment of Human Biology, NUTRIM, School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, Maastricht, The Netherlands.ORCID 0000-0002-5295-4223
Giang N LeDepartment of Medical Microbiology, Maastricht University Medical Center+, Maastricht, The Netherlands.ORCID 0000-0001-6660-557X
Marina FassarellaLaboratory of Microbiology, Wageningen University & Research, Wageningen, The Netherlands.ORCID 0000-0001-7285-0029
Dorien ReijndersDepartment of Human Biology, NUTRIM, School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, Maastricht, The Netherlands.ORCID 0000-0002-6637-4553
Gijs H GoossensDepartment of Human Biology, NUTRIM, School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, Maastricht, The Netherlands.ORCID 0000-0002-2092-3019
Erwin G ZoetendalLaboratory of Microbiology, Wageningen University & Research, Wageningen, The Netherlands.ORCID 0000-0002-7149-0727
John PendersDepartment of Medical Microbiology, Maastricht University Medical Center+, Maastricht, The Netherlands.ORCID 0000-0001-9146-5919
Ellen E BlaakDepartment of Human Biology, NUTRIM, School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, Maastricht, The Netherlands.ORCID 0000-0002-2496-3464
University Medical Center · USWageningen University & Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Detrimental consequences of antibiotic treatment may include long-lasting disruption of the gut microbiota. Previous studies found no negative effects of antibiotics on metabolic health, although individualized responses were observed. Here, we aimed to investigate the subject-specific response to vancomycin use in tissue-specific insulin sensitivity by stratifying individuals based on the presence of antibiotic resistance genes (ARGs) or opportunistic pathogens (OPs) in the baseline fecal microbiota. Quantitative Polymerase Chain Reaction (qPCR) was used to detect ARGs and OPs in DNA isolated from fecal samples of 56 males with overweight/obesity (Body Mass Index: 25-35 kg/m

Indexed as

Gastrointestinal MicrobiomeInsulin ResistanceAdipose TissueAnti-Bacterial AgentsBacterial ProteinsDrug Resistance, MicrobialHumansMaleVancomycinAnti-Bacterial AgentsBacterial ProteinsVancomycinadipose tissueAntibiotic resistancegut microbiomeinsulin sensitivitymetabolic healthobesityvanBvancomycin

Identifiers

PMID35695620
PMCPMC9196849
OpenAlexW4282552842

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.