Evidence map›Paper›PMID 35695553›Full record

ArticleAnnals of medicine2022

Prevalence and related factors of hyperuricaemia in Chinese children and adolescents: a pooled analysis of 11 population-based studies.

Jiahuan Rao, Peiyu Ye, Jie Lu, Bi Chen, Nan Li, Huiying Zhang, Hui Bo, Xinchun Chen, Huiting Liu, Chunhong Zhang and 6 more

Open access · goldAbstract read
In one paragraph

Article in Annals of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
8.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 1 country.

Jiahuan RaoCenter for Non-communicable Disease Management, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, PR China.
Peiyu YeCenter for Non-communicable Disease Management, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, PR China.
Jie LuDepartment of Endocrinology and Metabolism, Shandong Provincial Clinical Research Center for Immune Diseases and Gout, Shandong Provincial Key Laboratory of Metabolic Diseases, Qingdao Key Laboratory of Gout, the Affiliated Hospital of Qingdao University, Qingdao, PR China.
Bi ChenDepartment of Clinical Laboratory, the Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, PR China.
Nan LiTianjin Women's and Children's Health Center, Tianjin, PR China.
Huiying ZhangDepartment of Children's and Adolescent Health, Public Health College, Harbin Medical University, Harbin, PR China.
Hui BoDepartment of Pediatrics, Jinghai District Hospital, Jinghai Clinical College, Tianjin Medical University, Tianjin, PR China.
Xinchun ChenDepartment of Pediatrics, Tangshan People's Hospital, Tangshan, PR China.
Huiting LiuDepartment of pediatric, The First Hospital of Jinzhong, Shanxi, PR China.
Chunhong ZhangCancer Center, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Yunnan, PR China.
Hua WeiDivision of Rheumatology, Clinical Medical College, Yangzhou University, Jiangsu, PR China.
Qin WuDivision of Rheumatology, Clinical Medical College, Yangzhou University, Jiangsu, PR China.
Yinkun YanCenter for Non-communicable Disease Management, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, PR China.ORCID 0000-0002-7758-744X
Changgui LiDepartment of Endocrinology and Metabolism, Shandong Provincial Clinical Research Center for Immune Diseases and Gout, Shandong Provincial Key Laboratory of Metabolic Diseases, Qingdao Key Laboratory of Gout, the Affiliated Hospital of Qingdao University, Qingdao, PR China.
Jie MiCenter for Non-communicable Disease Management, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, PR China.
China Child and Adolescent Hyperuricemia Study (CCAHS) Consortium
Capital Medical University · CNQingdao University · CNYangzhou University · CNAffiliated Hospital of Jining Medical University · CNHarbin Medical University · CNKunming Medical University · CNSecond People 's Hospital of Jinzhong · CNTangshan People's Hospital · CNTianjin Children's Hospital · CNWenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsHyperuricaemia can lead to gout and is associated with an increased risk of cardiometabolic disease. We aimed to investigate the prevalence of hyperuricaemia and its related factors in Chinese children and adolescents.

methodsWe pooled data from 11 population-based studies comprising 54,580 participants aged 3-19 years. The sex- and age-standardized prevalence of hyperuricaemia was estimated overall and by sex, age, weight status, geographic region and survey year.

resultsSerum uric acid (SUA) increased gradually from 3 to 11 years with no significant sex difference, and then increased dramatically during 11-15 years. The estimated overall prevalence of hyperuricaemia was 23.3% (26.6% in boys and 19.8% in girls,

conclusionsThe prevalence of hyperuricaemia in Chinese children and adolescents is unexpectedly high. The findings suggest an urgent need to implement effective interventions to reduce risk of hyperuricaemia in Chinese youths.KEY MESSAGES

Indexed as

HyperuricemiaAdolescentChildChinaCross-Sectional StudiesFemaleHumansMaleObesityPrevalenceUric AcidUric AcidadolescentsChildrenhyperuricaemiaprevalenceuric acid

Identifiers

PMID35695553
PMCPMC9225777
OpenAlexW4282588738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.