Evidence map›Paper›PMID 35695030›Full record

ArticleBone & joint open2022

Failure analysis of articulating polymethyl methacrylate spacers in two-stage revision total hip arthroplasty.

Maxime Jaubert, Marie Le Baron, Christophe Jacquet, Antoine Couvreur, Maxime Fabre-Aubrespy, Xavier Flecher, Matthieu Ollivier, Jean-Noel Argenson

Open access · goldAbstract read
In one paragraph

Article in Bone & joint open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Periprosthetic joint infections: state-of-the-art.Archives of orthopaedic and trauma surgery · 2024
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Maxime JaubertInstitute for Locomotion, Department of Orthopedics and Traumatology, Northern Hospital, Marseille, France.ORCID 0000-0002-2906-2286
Marie Le BaronInstitute for Locomotion, Department of Orthopedics and Traumatology, Northern Hospital, Marseille, France.ORCID 0000-0002-8833-7454
Christophe JacquetInstitute for Locomotion, Department of Orthopedics and Traumatology ISM, CNRS, Aix-Marseille University, St. Marguerite Hospital, Marseille, France.
Antoine CouvreurInstitute for Locomotion, Department of Orthopedics and Traumatology ISM, CNRS, Aix-Marseille University, St. Marguerite Hospital, Marseille, France.
Maxime Fabre-AubrespyInstitute for Locomotion, Department of Orthopedics and Traumatology ISM, CNRS, Aix-Marseille University, St. Marguerite Hospital, Marseille, France.ORCID 0000-0003-0634-3568
Xavier FlecherInstitute for Locomotion, Department of Orthopedics and Traumatology, Northern Hospital, Marseille, France.ORCID 0000-0002-2229-3620
Matthieu OllivierInstitute for Locomotion, Department of Orthopedics and Traumatology ISM, CNRS, Aix-Marseille University, St. Marguerite Hospital, Marseille, France.
Jean-Noel ArgensonInstitute for Locomotion, Department of Orthopedics and Traumatology ISM, CNRS, Aix-Marseille University, St. Marguerite Hospital, Marseille, France.ORCID 0000-0003-0879-7803
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTwo-stage exchange revision total hip arthroplasty (THA) performed in case of periprosthetic joint infection (PJI) has been considered for many years as being the gold standard for the treatment of chronic infection. However, over the past decade, there have been concerns about its safety and its effectiveness. The purposes of our study were to investigate our practice, collecting the overall spacer complications, and then to analyze their risk factors.

methodsWe retrospectively included 125 patients with chronic hip PJI who underwent a staged THA revision performed between January 2013 and December 2019. All spacer complications were systematically collected, and risk factors were analyzed. Statistical evaluations were performed using the Student's

resultsOur staged exchange practice shows poor results, which means a 42% mechanical spacer failure rate, and a 20% recurrent infection rate over the two years average follow-up period. Moreover, we found a high rate of spacer dislocation (23%) and a low rate of spacer fracture (8%) compared to the previous literature. Our findings stress that the majority of spacer complications and failures is reflecting a population with high comorbid burden, highlighted by the American Society of Anesthesiology grade, Charlson Comorbidity Index, and Lee score associations, as well as the cardiac, pulmonary, kidney, or hepatic chronic conditions.

conclusionOur experience of a two-stage hip exchange revision noted important complication rates associated with high failure rates of polymethylmethacrylate spacers. These findings must be interpreted in the light of the patient's comorbidity profiles, as the elective population for staged exchange has an increasing comorbid burden leading to poor results. In order to provide better results for this specific population, our conclusion suggests that comparative strategy studies are required to improve our therapeutic indication. Cite this article:

Indexed as

Articulating spacerCharlson Comorbidity Index (CCI)ComplicationsFailureFischer's exact testhipHipinfectionmedical comorbiditiesPeriprosthetic joint infectionperiprosthetic joint infection (PJI)PMMApolymethyl methacrylatespacer fracturesStudent T-testTwo-stage exchangetwo-stage revision total hip arthroplasty

Identifiers

PMID35695030
PMCPMC9233427
OpenAlexW4282829723

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.