Evidence map›Paper›PMID 35694977›Full record

ReviewCNS oncology2022

Extranodal classical Hodgkin lymphoma involving the spinal cord: case report and review of the literature.

Katell Le Dû, Nicolas Alarion, Hassan Rabi, Olivier Casasnovas, Philippine Robert, Amandine Durand, Bénédicte Burlet, Claire Tabouret-Viaud, Selim Ramla, Laurent Martin and 1 more

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in CNS oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Katell Le DûDepartment of Hematology, Confluent Private Hospital, Nantes, France.ORCID 0000-0003-4371-2668
Nicolas AlarionNuclear Medecine, Institut Inter-RégionaL de Cancérologie Jean Bernard, Victor Hugo Medical Center, Le Mans, France.
Hassan RabiRadiologic Department, Maine Image Santé, Le Mans, France.
Olivier CasasnovasDepartment of Hematology, University Hospital Center, Dijon, France.
Philippine RobertDepartment of Hematology, University Hospital Center, Dijon, France.
Amandine DurandDepartment of Hematology, University Hospital Center, Dijon, France.
Bénédicte BurletINSERM UMR1231 UFR Bourgogne, Dijon, France.
Claire Tabouret-ViaudCentre G F Leclerc, Nuclear Medicine, Dijon, France.
Selim RamlaDepartment of Pathology, University Hospital Center, Dijon, France.
Laurent MartinDepartment of Hematology, University Hospital Center, Dijon, France.
Cédric RossiDepartment of Hematology, University Hospital Center, Dijon, France.
Inserm · FRCentre Georges François Leclerc · FRCentre Jean Bernard · FRHôpital privé du Confluent · FRLe Mans Université · FRMaison des Sciences sociales et des Humanités de Dijon · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary CNS involvement is very rare in Hodgkin lymphoma. Here we present two cases of spinal cord dissemination. Two women of 40 and 65 years of age presented symptoms of spinal cord injury; imaging showed an intramedullary mass in T10 and T2, respectively, without vertebral involvement and upper diaphragmatic lymph nodes. Lymph-node biopsy confirmed the diagnosis of classical Hodgkin lymphoma in both patients. The first patient received four cycles of chemotherapy (escalated BEACOPP and ABVD) with intrathecal therapy, and the second four cycles of doxorubicin, vinblastine, dacarbazine (AVD) and local irradiation after surgery decompression. Complete metabolic response was obtained at the end of treatment. After 5 and 7 years of follow-up respectively, neurological deficits persisted in both.

Indexed as

Hodgkin DiseaseAntineoplastic Combined Chemotherapy ProtocolsBleomycinDacarbazineDoxorubicinFemaleHumansSpinal CordVinblastineVincristineBleomycinDacarbazineDoxorubicinVinblastineVincristine18F-FDG PETcase reportclassical Hodgkin lymphomaradiotherapyspinal cord infiltrationsurgery

Identifiers

PMID35694977
PMCPMC9280417
OpenAlexW4282822223

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.