ArticleAging & mental health2023
The relationship between optimism, MCI, and dementia among postmenopausal women.
Article in Aging & mental health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Overlooked cases of mild cognitive impairment: Implications to early Alzheimer's disease.Ageing research reviews · 2024Pooled it
- Epigenetic clocks of biological aging and risk of incident mild cognitive impairment and dementia: the Women's Health Initiative Memory Study.medRxiv : the preprint server for health sciences · 2025Article
- Optimism and cognitive functioning trajectories in a cohort of aging men.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Moving Beyond Depression: Mood Symptoms Across the Spectrum Relate to Tau Pathology in Older Women at Risk for Alzheimer's Disease.International journal of aging & human development · 2025Article
- Physical health and cognitive ability factors in predicting retirement adjustment based on machine learning approach: results from the China Health and Retirement Longitudinal Study.Frontiers in psychology · 2025Article
- The mediating role of coping style in the relationship between optimism and cognitive impairment in patients with stroke.Frontiers in neurology · 2025Article
- Optimism, sleep quality, physical activity, and cancer-related cognitive impairment in middle-to-older aged patients undergoing breast cancer treatment.International journal of clinical and health psychology : IJCHPArticle
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
objectivesThe relationship between optimism and cognitive functioning is not fully understood. We examined the association of optimism with risk of mild cognitive impairment (MCI) and dementia in the Women's Health Initiative Memory Study (WHIMS).
methodsOptimism was measured by the Life Orientation Test-Revised (LOT-R) total score, and optimism and pessimism subscales. A panel of experts adjudicated cognitive endpoints based on annual cognitive assessments. We used cox proportional hazard regression models to examine the association of LOT-R total score and optimism and pessimism sub-scores with MCI/dementia. We also examined the relationship between vascular disease, LOT-R total score, optimism and pessimism, and cognition.
resultsMean age was 70.5 (SD = 3.9) years. The sample (
conclusionThese data suggest that less pessimism, but not more optimism, was associated with a lower risk of MCI and dementia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.