ArticleActa orthopaedica2022
Pain medication purchases before and after total hip and knee arthroplasty: a register study of 329,743 arthroplasties.
Article in Acta orthopaedica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 7 citations in OpenAlex.
- Purchases of analgesics before and after spine surgery - register based study of 152,829 Finnish patients with 15-year follow-up.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Factors Associated With the Risk of Neuropathic Pain One Year After Total Knee Arthroplasty and the Protective Role of Local Infiltration Analgesia: A Registry-Based Prospective Cohort Study.ACR open rheumatology · 2025Article
- Association between preoperative self-rated health and opioid use 12 months after total hip arthroplasty for osteoarthritis: a cohort study using Danish National Health Survey Data.Acta orthopaedica · 2025Article
- The impact of total joint arthroplasty on arterial stiffness in osteoarthritis patients: a 7-year prospective cohort study (CAMERA study).Scientific reports · 2025Article
- The long-term impacts of opioid use before and after joint arthroplasty: matched cohort analysis of New Zealand linked register data.Family practice · 2024Article
- Initial and Long-Term Prescribing of Opioids and Non-steroidal Anti-inflammatory Drugs Following Total Hip and Knee Arthroplasty.Geriatric orthopaedic surgery & rehabilitation · 2024Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeTotal hip (THA) and knee (TKA) arthroplasty are effective pain treatment in osteoarthritis; however, there are patients with long-term pain and in need of analgesics. We studied purchases of paracetamol, non-steroidal anti-inflammatory drugs (NSAIDs), opioids, and neuropathic pain medication before and after THA or TKA. PATIENTS AND
methodsWe searched all THA (n = 149,158) and TKA (n = 180,585) cases in Finland between the years 1998 and 2018 and the drug purchases made by patients during 1997-2018 using linked Finnish register data. Drug purchases were studied in 3-month periods.
resultsThe purchases of all analgesics increased from 3 years before operation to 3 months before operation. Around the time of THA or TKA, the purchases of all analgesics spiked to 7-56%, depending on drug. The purchases of all analgesics decreased rapidly during the first 6 months postoperatively. Purchases of paracetamol, NSAIDs, and opioids at 6 months postoperatively (6-23%) were lower than they were at 3 months preoperatively. At 3 years postoperatively, only paracetamol purchases were lower (15-18%) postoperatively than they were 3 years before arthroplasty. NSAID, opioid, and neuropathic pain medication purchases remained higher (4-14%).
interpretationTHA and TKA stop and reduce the preoperative increases in purchases of paracetamol, NSAIDs, and opioids. The purchases of pain medications by THA and TKA patients 1 year after operation are close to those in the general population.
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