Evidence map›Paper›PMID 35694717›Full record

Trial reportPrecision clinical medicine2022

Patient-directed vs. fixed-volume PEG for colonoscopy preparation: a randomized controlled trial.

Jixiang Zhang, Xuemei Jia, Yuanmei Guo, Haotian Jiang, Jiaming Hu, Siwei Wang, Binglu Huang, Wenhao Su, Jun Liu, Xiaoli Wang and 1 more

Open access · diamondAbstract readClinical Trial
In one paragraph

Trial report in Precision clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Precision medicine in inflammatory bowel disease.Precision clinical medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Jixiang ZhangDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Xuemei JiaDepartment of Hematology, Huashan Hospital of Fudan University, Shanghai 200433, China.
Yuanmei GuoDepartment of Hematology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Haotian JiangDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Jiaming HuDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Siwei WangDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Binglu HuangDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Wenhao SuDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Jun LiuDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Xiaoli WangDepartment of Plastic Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Weiguo DongDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Renmin Hospital of Wuhan University · CNWuhan University · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Individualization using different volumes of polyethylene glycol is widely regarded as the optimal solution for bowel preparation, while the patient-directed regimen we propose may serve as a reliable individual solution. This study aimed to assess the efficacy, safety, and satisfaction of bowel preparation with a patient-directed regimen. Methods: Patients in the fixed-volume group ingested the same amount of PEG, while those in patient-directed group ingested different amount according to stool consistency or stool water content. Results: After filtering by exclusion criteria, 428 individuals in the fixed-volume group and 103 in the patient-directed group were successfully enrolled and analyzed. Eighty-three (80.6%) individuals in the patient-directed group had a reduced polyethylene glycol volume. There was no significant difference in the bowel preparation efficacy between the two groups (90.0% vs. 90.3%, χ² = 0.01; Conclusions: Without decreasing the bowel preparation efficacy, the patient-directed regimen increased the safety and satisfaction of bowel preparation and is expected to be a regular and individual solution for bowel preparation. Individuals with a lower body mass index are more likely to undertake this new regimen. Trial registration number: ChiCTR1900022072 at ChiClinicalTrials.gov.

Indexed as

bowel preparationefficacyindividualizationpatient-directedsafety

Identifiers

PMID35694717
PMCPMC9172656
OpenAlexW4221081407

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.