Evidence map›Paper›PMID 35694677›Full record

SynthesisFrontiers in cardiovascular medicine2022

Isolated Coarctation of the Aorta: Current Concepts and Perspectives.

Ami B Bhatt, Maria R Lantin-Hermoso, Curt J Daniels, Robert Jaquiss, Benjamin John Landis, Bradley S Marino, Rahul H Rathod, Robert N Vincent, Bradley B Keller, Juan Villafane

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Visualization of the Embryonic Great Vessels Using Plastic Resin Injection.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  3. Late Complications After Aortic Coarctation Repair.Journal of cardiovascular development and disease · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 1 country.

Ami B BhattDepartments of Internal Medicine and Pediatrics and Division of Cardiology, Harvard Medical School, Boston, MA, United States.
Maria R Lantin-HermosoSection of Cardiology, Department of Pediatrics, Baylor College of Medicine, Houston, TX, United States.
Curt J DanielsDepartments of Pediatrics and Internal Medicine, The Ohio State University Medical Center, Columbus, OH, United States.
Robert JaquissDepartment of Cardiovascular and Thoracic Surgery and Department of Pediatrics, UT Southwestern Medical Center, Dallas, TX, United States.
Benjamin John LandisDepartment of Pediatrics and Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, United States.
Bradley S MarinoDepartment of Pediatric Cardiology, Cleveland Clinic Children's, Cleveland, OH, United States.
Rahul H RathodDepartment of Pediatrics, Harvard Medical School, Boston, MA, United States.
Robert N VincentDepartment of Pediatrics, New York Medical College, Valhalla, NY, United States.
Bradley B KellerCincinnati Children's Heart Institute and the Department of Pediatrics, University of Cincinnati, Cincinnati, OH, United States.
Juan VillafaneCincinnati Children's Heart Institute and the Department of Pediatrics, University of Cincinnati, Cincinnati, OH, United States.
Cincinnati Children's Hospital Medical Center · USHarvard University · USBaylor College of Medicine · USCleveland Clinic · USIndiana University School of MedicineNew York Medical College · USThe Ohio State University Wexner Medical Center · USThe University of Texas Southwestern Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current management of isolated CoA, localized narrowing of the aortic arch in the absence of other congenital heart disease, is a success story with improved prenatal diagnosis, high survival and improved understanding of long-term complication. Isolated CoA has heterogenous presentations, complex etiologic mechanisms, and progressive pathophysiologic changes that influence outcome. End-to-end or extended end-to-end anastomosis are the favored surgical approaches for isolated CoA in infants and transcatheter intervention is favored for children and adults. Primary stent placement is the procedure of choice in larger children and adults. Most adults with treated isolated CoA thrive, have normal daily activities, and undergo successful childbirth. Fetal echocardiography is the cornerstone of prenatal counseling and genetic testing is recommended. Advanced 3D imaging identifies aortic complications and myocardial dysfunction and guides individualized therapies including re-intervention. Adult CHD program enrollment is recommended. Longer follow-up data are needed to determine the frequency and severity of aneurysm formation, myocardial dysfunction, and whether childhood lifestyle modifications reduce late-onset complications.

Indexed as

adult congenital heart diseasecatheter interventioncoarctation of the aortacongenital heart diseaseheart surgery

Identifiers

PMID35694677
PMCPMC9174545
OpenAlexW4281487063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.