ArticleACS omega2022
Crosslinked Chitosan-Gelatin Biocompatible Nanocomposite as a Neuro Drug Carrier.
Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 88 citations in OpenAlex.
- Flexible Catechol-Conjugated Chitosan/Gelatin Bilayer Patches for Topical Hemostasis in Laparoscopic Surgery.ACS omega · 2026Article
- Article
- Engineering Metal-Organic Framework-Biopolymer-Based Hydrogels for Therapeutic Delivery.ACS materials Au · 2026Article
- Quaternized Chitosan Crosslinked Networks for pH-Responsive Macromolecule Delivery: A Review.Polymers · 2026Review
- Synthesis and characterization of electroactive chitosan/gelatin/PEDOT:PSS hydrogels with mixed ionic-electronic conductivity for potential wound healing applications.RSC advances · 2026Article
- Gelatin-Incorporated Chitosan-TPP Nanocomposites Enhanced Cumulative and Sustained Bovine Serum Albumin Release.ACS omega · 2026Article
- Synergistic and Intelligent Hydrogel for Conducting Osteoblast Proliferation: Synthesis, Characterization, and Multifunctional Properties.Gels (Basel, Switzerland) · 2025Article
- Structural and ion transport characteristics of transparent proton conducting biopolymer electrolytes based on chitosan and cold water fish skin gelatin.Scientific reports · 2025Article
- A Review of Chitosan-Based Electrospun Nanofibers for Food Packaging: From Fabrication to Function and Modeling Insights.Nanomaterials (Basel, Switzerland) · 2025Review
- Article
- Advancements in Hydrogels: A Comprehensive Review of Natural and Synthetic Innovations for Biomedical Applications.Polymers · 2025Review
- Modulation of Structural and Physical-Chemical Properties of Fish Gelatin Hydrogel by Natural Polysaccharides.International journal of molecular sciences · 2025Article
- Injectable Thermosensitive Thiol-Modified NIPAAm-ACS omega · 2025Article
- Physical and Structural Properties of Chitosan-Squid Gelatin Hydrogels.Gels (Basel, Switzerland) · 2025Article
- An Overview of Potential Applications of Environmentally Friendly Hybrid Polymeric Materials.Polymers · 2025Review
- Chitosan-Type-A-Gelatin Hydrogels Used as Potential Platforms in Tissue Engineering for Drug Delivery.Gels (Basel, Switzerland) · 2024Article
- Assessment of Chitosan/Gelatin Blend Enriched with Natural Antioxidants for Antioxidant Packaging of Fish Oil.Antioxidants (Basel, Switzerland) · 2024Article
- Gelatin-Zinc Carrier as a New Method of Targeted and Controlled Release of Risedronate.Materials (Basel, Switzerland) · 2024Article
- MFGE8 in exosomes derived from mesenchymal stem cells prevents esophageal stricture after endoscopic submucosal dissection in pigs.Journal of nanobiotechnology · 2024Article
- 3D-Printed Chitosan-Based Scaffolds withPharmaceutics · 2024Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The polymers, chitosan, a polysaccharide, and gelatin, a protein, are crosslinked in different ratios without the aid of a crosslinking agent. Facile chemical reactions were followed to synthesize a chitosan/gelatin nanocomposite in three different ratios (1:1, 1:3, and 3:1). The solubility of chitosan and the stability of gelatin were improved due to the crosslinking. Both the polymers have excellent biodegradability, biocompatibility, adhesion, and absorption properties in a biological environment. The properties of the composite were favorable to be used in drug delivery applications, and the drug dopamine was encapsulated in the composite for all three ratios. The properties of the chitosan/gelatin nanocomposite and dopamine-loaded chitosan/gelatin nanocomposite were examined using XRD, FTIR, SEM, UV, TGA, TEM, and DLS techniques, and the crosslinking was confirmed. Higuchi kinetic release was seen with a cumulative release of 93% within 24 h for the 1:3 nanocomposite in a neutral medium. The peaks at 9 and 20° in the XRD spectrum confirmed the encapsulation of dopamine with the increase in the crystallinity of chitosan, which is also evident from the SAED image. The dopamine functional groups were confirmed from the IR peaks between 500 and 1500 cm
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.