Evidence map›Paper›PMID 35694484›Full record

ArticleACS omega2022

tREPs-A New Class of Functional tRNA-Encoded Peptides.

Amrita Chakrabarti, Monika Kaushik, Juveria Khan, Deepanshu Soota, Kalairasan Ponnusamy, Sunil Saini, Siddharth Manvati, Jhalak Singhal, Anand Ranganathan, Soumya Pati and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Amrita ChakrabartiDepartment of Life Sciences, Shiv Nadar University, Greater Noida 201314, Uttar Pradesh, India.
Monika KaushikSchool of Biotechnology, Jawaharlal Nehru University, New Delhi 110067, India.
Juveria KhanSchool of Biotechnology, Jawaharlal Nehru University, New Delhi 110067, India.
Deepanshu SootaNational Centre for Biological Sciences, Bangalore 560065, India.
Kalairasan PonnusamyNational Centre for Disease Control, New Delhi 110054, India.
Sunil SainiDepartment of Biophysics, All India Institute of Medical Sciences, New Delhi 110029, India.
Siddharth ManvatiSchool of Biotechnology, Jawaharlal Nehru University, New Delhi 110067, India.
Jhalak SinghalSpecial Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi 110067, India.
Anand RanganathanSpecial Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi 110067, India.
Soumya PatiDepartment of Life Sciences, Shiv Nadar University, Greater Noida 201314, Uttar Pradesh, India.
Pawan Kumar DharSchool of Biotechnology, Jawaharlal Nehru University, New Delhi 110067, India.ORCID https://orcid.org/0000-0002-4032-7679
Shailja SinghSpecial Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi 110067, India.ORCID https://orcid.org/0000-0001-5286-6605
Jawaharlal Nehru University · INAll India Institute of Medical Sciences · INNational Center for Disease Control · INNational Centre for Biological Sciences · INShiv Nadar University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We asked if transfer RNA (tRNA) ever got an opportunity of translating its own sequence during evolution, what would have been the function of such tRNA-encoded peptides (tREPs)? If not, could one artificially synthesize tREPs to study the corresponding functional outcomes? Here, we report a novel, first-in-the-class, chemically synthesized tREP-18 molecule originating from the

Identifiers

PMID35694484
PMCPMC9178612
OpenAlexW4281483996

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.