Evidence map›Paper›PMID 35694224›Full record

ArticleFrontiers in bioengineering and biotechnology2022

Local Administration of Ginkgolide B Using a Hyaluronan-Based Hydrogel Improves Wound Healing in Diabetic Mice.

Limei Wang, Kedi Xia, Lu Han, Min Zhang, Jihuan Fan, Liu Song, Anqi Liao, Wenyu Wang, Jianfeng Guo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Limei WangDepartment of Pharmacy, Jilin Province FAW General Hospital, Changchun, China.
Kedi XiaDepartment of Pharmacy, Jilin Province FAW General Hospital, Changchun, China.
Lu HanDepartment of Medical Administration, Jilin Province FAW General Hospital, Changchun, China.
Min ZhangDepartment of Ophthalmology and Otorhinolaryngology, Jilin Province FAW General Hospital, Changchun, China.
Jihuan FanDepartment of Education and Science Services, Jilin Province FAW General Hospital, Changchun, China.
Liu SongSchool of Pharmaceutical Sciences, Jilin University, Changchun, China.
Anqi LiaoSchool of Pharmaceutical Sciences, Jilin University, Changchun, China.
Wenyu WangDepartment of Thoracic Surgery, Jilin Province FAW General Hospital, Changchun, China.
Jianfeng GuoSchool of Pharmaceutical Sciences, Jilin University, Changchun, China.
Jilin University · CNJilin Province Tumor Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The delayed and incomplete healing of diabetic wounds remains a major concern of global healthcare. The complex biological processes within the diabetic wound, such as chronic inflammation, impaired blood vessel growth and immature collagen remodeling, dramatically cause the failure of current treatments. Thus, emerging therapeutic strategies are highly desirable. Ginkgolide B (GB, a natural product extracted from the leaves of Ginkgo biloba L.) has been applied in the treatment of cerebrovascular and cardiovascular disorders, which is mainly due to the anti-oxidative, anti-inflammatory and proliferative effects. In this study, the role of GB in facilitating the anti-inflammatory and pro-healing effects on diabetic wounds was for the first time confirmed using

Indexed as

biomaterialsdrug deliveryhyaluronic acidnatural productsregenerative medicine

Identifiers

PMID35694224
PMCPMC9174682
OpenAlexW4285740134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.