Evidence map›Paper›PMID 35694196›Full record

ArticleWellcome open research2022

Anti-TNF therapy for inflammatory bowel disease in patients with neurodegenerative Niemann-Pick disease Type C.

Isabelle Williams, Sumeet Pandey, Wolfram Haller, Hien Quoc Huynh, Alicia Chan, Gesche Düeker, Ruth Bettels, Laurent Peyrin-Biroulet, Chinenye R Dike, Catherine DeGeeter and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Wellcome open research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 6 countries.

Isabelle WilliamsTranslational Gastroenterology Unit, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0001-5765-5321
Sumeet PandeyTranslational Gastroenterology Unit, University of Oxford, Oxford, UK.
Wolfram HallerBirmingham Children's Hospital, UK, Birmingham, UK.
Hien Quoc HuynhDepartment of Paediatrics, Stollery Children's Hospital, University of Alberta, Alberta, Canada.
Alicia ChanDivision of Clinical Genetics, Stollery Children's Hospital, University of Alberta, Alberta, Canada.
Gesche DüekerUniversity Children's Hospital Bonn, Bonn, Germany.
Ruth BettelsChildren's Hospital Munster, Munster, Germany.
Laurent Peyrin-BirouletInserm U1256 NGERE, 8 Lorraine University, Vandoeuvre-les-Nancy, France.
Chinenye R DikeStead Family Department of Pediatrics, University of Iowa, Iowa, USA.
Catherine DeGeeterStead Family Department of Pediatrics, University of Iowa, Iowa, USA.ORCID https://orcid.org/0000-0001-8762-0613
David SmithDepartment of Pharmacology, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0002-9845-5913
Nada Al EisaDepartment of Pharmacology, University of Oxford, Oxford, UK.
Nick PlattDepartment of Pharmacology, University of Oxford, Oxford, UK.
Thorsten MarquardtChildren's Hospital Munster, Munster, Germany.
Tobias SchwerdDepartment of Paediatrics, Dr. von Hauner Children's Hospital, Munich, Germany.
Frances M PlattDepartment of Pharmacology, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0001-7614-0403
Holm H UhligTranslational Gastroenterology Unit, University of Oxford, Oxford, UK.
University of Oxford · GBUniversity Hospital Münster · DEUniversity of Alberta · CAUniversity of Iowa · USBirmingham Children's Hospital · GBInserm · FRKing Saud bin Abdulaziz University for Health Sciences · SAMünchen Klinik · DEUniversity Hospital Bonn · DE

Funding

Wellcome Trust 202834/Z/16/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Niemann-Pick disease Type C1

Identifiers

PMID35694196
PMCPMC9171292
OpenAlexW4205958713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.