ReviewPrecision clinical medicine2018
Regulative role of the CXCL13-CXCR5 axis in the tumor microenvironment.
Review in Precision clinical medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Cytokines and chemokines in plasma as markers reflecting immunophenotype of head and neck squamous cell carcinoma.Human cell · 2026Article
- Neoadjuvant Immunochemotherapy Increases the Abundance of Tertiary Lymphoid Structures and Lymphocyte Subpopulations Is Associated With Prognosis of Esophageal Squamous Cell Carcinoma.Cancer medicine · 2026Article
- Multi-omics analysis of Helicobacter pylori-associated gastric cancer identifies hub genes as a novel therapeutic biomarker.Briefings in bioinformatics · 2025Article
- Prognostic impact and landscape of cellular CXCR5 chemokine receptor expression in clear-cell renal cell carcinoma.Cancer immunology, immunotherapy : CII · 2025Article
- Ex Vivo Model of Breast Cancer Cell Invasion in Live Lymph Node Tissue.ACS pharmacology & translational science · 2025Article
- Essential roles of B cell subsets in the progression of MASLD and HCC.JHEP reports : innovation in hepatology · 2024Article
- Serum CXCL13 as a Novel Biomarker in Oral Squamous Cell Carcinoma.Cancer medicine · 2024Article
- Ex vivo model of breast cancer cell invasion in live lymph node tissue.bioRxiv : the preprint server for biology · 2024Article
- Intracellular Adhesion Molecule-1 Improves Responsiveness to Immune Checkpoint Inhibitor by Activating CD8Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Inflammation in Urological Malignancies: The Silent Killer.International journal of molecular sciences · 2023Review
- The Diagnostic Significance of CXCL13 in M2 Tumor Immune Microenvironment of Human Astrocytoma.Pathology oncology research : POR · 2022Article
- CXCR5Frontiers in medicine · 2022Review
- CXC chemokine ligand-13 promotes metastasis via CXCR5-dependent signaling pathway in non-small cell lung cancer.Journal of cellular and molecular medicine · 2021Article
- CXCL13 expression in mouse 4T1 breast cancer microenvironment elicits antitumor immune response by regulating immune cell infiltration.Precision clinical medicine · 2021Article
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- The N-terminal length and side-chain composition of CXCL13 affect crystallization, structure and functional activity.Acta crystallographica. Section D, Structural biology · 2020Article
- High dose-rate brachytherapy of localized prostate cancer converts tumors from cold to hot.Journal for immunotherapy of cancer · 2020Article
- Article
- M1 Polarization Markers Are Upregulated in Basal-Like Breast Cancer Molecular Subtype and Associated With Favorable Patient Outcome.Frontiers in immunology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chemokines are best known for their abilities of recruiting immune cells and forming lymphoid tissue. Through interactions between chemokines and their receptors, various immune cell subsets are recruited into the tumor microenvironment which is the primary location for tumor cells interacting with responding host cells. In recent decades, a large volume of studies have revealed chemokines' role in the tumor microenvironment in regulating tumor growth, invasion, and/or metastasis as well as tumor immune response; however, their molecular mechanisms are not well understood. Recently, increasing evidence has reported the importance of the CXCL13-CXCR5 axis in the tumor microenvironment of various human malignancies. Thus, in this review, we will focus on the CXCL13-CXCR5 axis and elaborate on the expression patterns, regulating and corresponding regulatory mechanisms as well as clinical values in a wide range of human cancers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.