Evidence map›Paper›PMID 35693826›Full record

ArticleFrontiers in immunology2022

HA/CD44 Regulates the T Helper 1 Cells Differentiation by Activating Annexin A1/Akt/mTOR Signaling to Drive the Pathogenesis of EAP.

Jing Chen, Jialin Meng, Xiaoling Li, Xiao Li, Yi Liu, Chen Jin, Li Zhang, Zongyao Hao, Xianguo Chen, Meng Zhang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

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  9. Albumin Nanoparticle-Based Drug Delivery Systems.International journal of nanomedicine · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Jing ChenDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Jialin MengDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Xiaoling LiDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Xiao LiDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Yi LiuDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Chen JinDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Li ZhangDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Zongyao HaoDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Xianguo ChenDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Meng ZhangDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Chaozhao LiangDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Anhui Medical University · CNFirst Affiliated Hospital of Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD44 partcipates in multiple inflammatory reactions. Here, we aimed to investigate the role of CD44 and the ligand, hyaluronan (HA), on chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) pathogenesis. We found that CD44 was universally expressed in CD4

Indexed as

Annexin A1Chronic PainProstatitisHumansHyaluronan ReceptorsHyaluronic AcidInflammationMalePelvic PainProto-Oncogene Proteins c-aktTh1 CellsTOR Serine-Threonine KinasesAnnexin A1CD44 protein, humanHyaluronan ReceptorsHyaluronic AcidMTOR protein, humanProto-Oncogene Proteins c-aktTOR Serine-Threonine KinasesANX A1CD44chronic prostatitis/chronic pelvic pain syndromehyaluronanTh1 cells

Identifiers

PMID35693826
PMCPMC9178196
OpenAlexW4281550190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.